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A cholinergic neuron is a nerve cell which mainly uses the neurotransmitter acetylcholine (ACh) to send its messages. Many neurological systems are cholinergic.Cholinergic neurons provide the primary source of acetylcholine to the cerebral cortex, and promote cortical activation during both wakefulness and rapid eye movement sleep. [1]
Cholinergic agents are compounds which mimic the ... A receptor is cholinergic if it uses acetylcholine as its neurotransmitter. [2] A synapse is cholinergic if it ...
Acetylcholine (ACh) is an organic compound that functions in the brain and body of many types of animals (including humans) as a neurotransmitter. [1] Its name is derived from its chemical structure: it is an ester of acetic acid and choline. [2] Parts in the body that use or are affected by acetylcholine are referred to as cholinergic.
A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse.The cell receiving the signal, or target cell, may be another neuron, but could also be a gland or muscle cell.
Chemical synapses can be classified according to the neurotransmitter released: glutamatergic (often excitatory), GABAergic (often inhibitory), cholinergic (e.g. vertebrate neuromuscular junction), and adrenergic (releasing norepinephrine).
Very few parts of the sympathetic system use cholinergic receptors. In sweat glands the receptors are of the muscarinic type. The sympathetic nervous system also has some preganglionic nerves terminating at the chromaffin cells in the adrenal medulla , which secrete epinephrine and norepinephrine into the bloodstream.
The nAChR is found at the edges of junctional folds at the neuromuscular junction on the postsynaptic side; it is activated by acetylcholine release across the synapse. The diffusion of Na + and K + across the receptor causes depolarization, the end-plate potential, that opens voltage-gated sodium channels , which allows for firing of the ...
In humans, AChE is a cholinergic enzyme involved in the hydrolysis of the neurotransmitter acetylcholine (ACh) into its constituents, choline, and acetate. [20] Overall, in mammals, AChE is primarily involved in the termination of impulse transmission at cholinergic synapses by rapid hydrolysis of the neurotransmitter acetylcholine. [20]