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Styrene is regarded as a "known carcinogen", especially in case of eye contact, but also in case of skin contact, of ingestion and of inhalation, according to several sources. [20] [33] [34] [35] Styrene is largely metabolized into styrene oxide in humans, resulting from oxidation by cytochrome P450.
Residents near Cleves are being urged to leave their homes Tuesday afternoon because a rail car is leaking styrene. What to know about the chemical.
Humans are exposed to toxic chemicals and microplastics at all stages in the plastics life cycle. Microplastics effects on human health are of growing concern and an area of research. The tiny particles known as microplastics (MPs), have been found in various environmental and biological matrices, including air, water, food, and human tissues.
Styrene oxide is a main metabolite of styrene in humans or animals, resulting from oxidation by cytochrome P450. It is considered possibly carcinogenic from gavaging significant amounts into mice and rats. [4] Styrene oxide is subsequently hydrolyzed in vivo to styrene glycol by epoxide hydrolase. [5]
In August 2005, styrene began leaking from a railcar in Cincinnati's East End. That also was not the result of a derailment, but the leak forced evacuations and shelter-in-place orders for residents.
Average levels of daily exposure are below the levels deemed to be unsafe, but more research needs to be done on the effects of low dose exposure on humans. A lot is unknown on how severely humans are physically affected by these chemicals. Some of the chemicals used in plastic production can cause dermatitis upon contact with human skin. In ...
Side effects in humans [ edit ] The American Conference of Governmental Industrial Hygienists (2009) defined occupational exposure limits of 10 ppm for airborne concentrations of a-methylstyrene.
Animals do not recognize polystyrene foam as an artificial material and may even mistake it for food. [71] Polystyrene foam blows in the wind and floats on water due to its low specific gravity. It can have serious effects on the health of birds and marine animals that swallow significant quantities. [71]