Search results
Results from the WOW.Com Content Network
Gestational choriocarcinoma is a form of gestational trophoblastic neoplasia, which is a type of gestational trophoblastic disease (GTD), that can occur during pregnancy. It is a rare disease where the trophoblast , a layer of cells surrounding the blastocyst , undergoes abnormal developments, leading to trophoblastic tumors .
Since gestational choriocarcinoma (which arises from a hydatidiform mole) contains paternal DNA (and thus paternal antigens), it is exquisitely sensitive to chemotherapy. The cure rate, even for metastatic gestational choriocarcinoma, is more than 90% when using chemotherapy for invasive mole and choriocarcinoma.
Gestational trophoblastic disease (GTD) is a term used for a group of pregnancy-related tumours. [1] These tumours are rare, and they appear when cells in the womb start to proliferate uncontrollably. The cells that form gestational trophoblastic tumours are called trophoblasts and come from tissue that grows to form the placenta during pregnancy.
The choriocarcinoma has 2 significant subtypes including gestational and non-gestational and they are differentiated by their different biological feature and prognosis. [4] Signs and symptoms of GTN will appear vary from person to person and depending upon the type of the disease.
Immunohistochemistry often shows positive staining for hPL, [4] [5] keratin, [5] Mel-CAM, [5] and EGFR., [4] This immunohistochemical profile, particularly the strong positivity for hPL and Mel-CAM, along with the negative or focal staining for β-hCG and p63, helps distinguish PSTT from other types of gestational trophoblastic neoplasia such as choriocarcinoma and epithelioid trophoblastic ...
Gestational trophoblastic disease is a pregnancy-associated concept, forming from the villous and extravillous trophoblast cells in the placenta. [ 8 ] Choriocarcinoma are trophoblastic tumors that form in the uterus from villous cells.
gestational uterine corpus choriocarcinoma: Human disease mediastinum choriocarcinoma: Human disease vulvar squamous cell carcinoma with tumor giant cells: Human disease gastric choriocarcinoma: A malignant germ cell tumor that arises from the stomach. It is characterized by the presence of syncytiotrophoblast and cytotrophoblast cellular ...
Theca lutein cysts occur almost exclusively in pregnancy and have an increased incidence in pregnancies complicated by gestational trophoblastic disease. [8] But additionally, theca lutein cysts may develop in conditions such as placentomegaly that may accompany diabetes, anti-D alloimmunization, mutifetal gestation, and individuals undergoing ...