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Less than 1% of patients have the following side effects: burning or itching of penis of sexual partner; polyuria; vulvar itching, soreness, edema, or discharge. [10] [7] [17] Clotrimazole creams and suppositories contain oil which may weaken latex condoms and diaphragms .
Alkylation of imidazole (2) with bromoketone (1) prepared from o,p-dichloroacetophenone affords the displacement product (3). Reduction of the ketone with sodium borohydride gives the corresponding alcohol ( 4 ).
Topical steroids are the topical forms of corticosteroids.Topical steroids are the most commonly prescribed topical medications for the treatment of rash and eczema.Topical steroids have anti-inflammatory properties and are classified based on their skin vasoconstrictive abilities. [1]
In general, use a potent preparation short term and weaker preparation for maintenance between flare-ups. While there is no proven best benefit-to-risk ratio, [11] if prolonged use of a topical steroid on a skin surface is required, a pulse therapy should be undertaken.
An antiseptic (Greek: ἀντί, romanized: anti, lit. 'against' [1] and σηπτικός, sēptikos, 'putrefactive' [2]) is an antimicrobial substance or compound that is applied to living tissue to reduce the possibility of sepsis, infection, or putrefaction.
It is applied to the skin or vagina as a cream or ointment. [2] [3] Common side effects include itchiness or irritation of the area in which it was applied. [2] Use in pregnancy is believed to be safe for the baby. [4] Miconazole is in the imidazole family of medications. [2]
The drug is generally well tolerated. The only common side effect is nausea (in 2% of patients). Less common side effects (<1%) include headache, increased or lowered blood cell counts (granulocytopenia, anaemia, lymphocytosis, monocytosis), increased liver enzymes, and allergic reactions. [1]
Common side effects include skin irritation, dry skin, redness, pimples, and telangiectasia. [8] Serious side effects may include adrenal suppression, allergic reactions, cellulitis, and Cushing's syndrome. [8] Use in pregnancy and breastfeeding is of unclear safety. [12] Clobetasol is believed to work by activating steroid receptors. [8]
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