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For sufficiently small Δt, r(t)Δt is the average number of spikes occurring between times t and t+Δt over multiple trials. If Δt is small, there will never be more than one spike within the interval between t and t+Δt on any given trial. This means that r(t)Δt is also the fraction of trials on which a spike occurred between those times.
A network that connects at neuron and synaptic level falls into the microscale. If the neurons are grouped into population of columns and minicolumns, the level is defined as mesoscale. The macroscale representation considers the network as regions of the brain connected by inter-regional pathways.
The nervous system is divided by neurologists into two parts: the central nervous system (which consists of the brain and spinal cord) and the peripheral nervous system (which consists of cranial and spinal nerves along with their associated ganglia). While the peripheral nervous system has an intrinsic ability for repair and regeneration, the ...
A biological neural network is composed of a group of chemically connected or functionally associated neurons. [2] A single neuron may be connected to many other neurons and the total number of neurons and connections in a network may be extensive.
The NEURON software, developed at Duke University, is a simulation environment for modeling individual neurons and networks of neurons. [25] The NEURON environment is a self-contained environment allowing interface through its GUI or via scripting with hoc or python. The NEURON simulation engine is based on a Hodgkin–Huxley type model using a ...
Functional integration is the study of how brain regions work together to process information and effect responses. Though functional integration frequently relies on anatomic knowledge of the connections between brain areas, the emphasis is on how large clusters of neurons – numbering in the thousands or millions – fire together under various stimuli.
After the techniques of multielectrode recordings were introduced, the task of real-time decoding of information from large neuronal ensembles became feasible. If, as Georgopoulos showed, just a few primary motor neurons could accurately predict hand motion in two planes, reconstruction of the movement of an entire limb should be possible with enough simultaneous recordings.
Neuronal self-avoidance, or isoneural avoidance, is an important property of neurons which consists in the tendency of branches (dendrites and axons) arising from a single soma (also called isoneuronal or sister branches) to turn away from one another.