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Benzamide is an organic compound with the chemical formula of C 7 H 7 NO. It is the simplest amide derivative of benzoic acid . In powdered form, it appears as a white solid, while in crystalline form, it appears as colourless crystals. [ 5 ]
Cinitapride (trade names Cintapro, Pemix) is a gastroprokinetic agent and antiemetic agent of the benzamide class which is marketed in India, Mexico, Pakistan and Spain. [ 1 ] [ 2 ] It acts as an agonist of the 5-HT 1 and 5-HT 4 receptors and as an antagonist of the 5-HT 2 receptors .
3-Aminobenzamide is an inhibitor of poly ADP ribose polymerase (PARP), an enzyme responsible for DNA repair, transcription control, and programmed cell death. [1] When PARP is activated it rapidly uses up stores of nicotinamide adenine dinucleotide (NAD +) in the cell as it performs DNA repair.
3,4,5-trimethoxy-benzamide. ... C 21 H 28 N 2 O 5: Molar mass: 388.464 g·mol −1: 3D model ... with 2-dimethylaminoethyl chloride affords the ether (2). Reductive ...
U-77891 is an opioid analgesic drug that was first synthesized in 1983 by the Upjohn company. [1] It was originally synthesized to prove that the removal of a single methylene spacer of the benzamide would alter a κ-opioid receptor agonist such as U-50488 into an μ-opioid receptor agonist, as well as producing a semi-rigid derivative of U-47700.
CAS Number : 127-71-9; ChemSpider ... DTXSID7045287; ECHA InfoCard: 100.004.419: Chemical and physical data; Formula: C 13 H 12 N 2 ... Text is available under the ...
Sultopride (trade names Barnetil, Barnotil, Topral) is an atypical antipsychotic of the benzamide chemical class used in Europe, Japan, and Hong Kong for the treatment of schizophrenia. [2] [3] [4] It was launched by Sanofi-Aventis in 1976. [2] Sultopride acts as a selective D 2 and D 3 receptor antagonist. [5]
Benzonitrile is a useful solvent and a versatile precursor to many derivatives. It reacts with amines to afford N-substituted benzamides after hydrolysis. [3] It is a precursor to diphenylmethanimine via reaction with phenylmagnesium bromide followed by methanolysis.