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XLR-11 (5"-fluoro-UR-144 or 5F-UR-144) is a drug that acts as a potent agonist for the cannabinoid receptors CB 1 and CB 2 with EC 50 values of 98 nM and 83 nM ...
AM-679 was one of the first 3-(2-iodobenzoyl)indole derivatives that was found to have significant cannabinoid receptor affinity, and while AM-679 itself has only modest affinity for these receptors, it was subsequently used as a base to develop several more specialised cannabinoid ligands that are now widely used in research, including the ...
Compared to THC, which is a partial agonist at CB 1 receptors, JWH-018, and many synthetic cannabinoids, are full agonists. JWH-018 may cause intense anxiety, agitation, and in rare cases, has been assumed to have been the cause of seizures and convulsions. JWH-018 and analogs of it may present serious dangers to the user when used to excess. [22]
JWH-147 is an analgesic drug used in scientific research, which acts as a cannabinoid agonist at both the CB 1 and CB 2 receptors. It is somewhat selective for the CB 2 subtype, with a K i of 11.0 nM at CB 1 vs 7.1 nM at CB 2. [1] It was discovered and named after the renowned professor of organic chemistry John W. Huffman.
Download QR code; Print/export Download as PDF; Printable version; In other projects ... is a synthetic cannabinoid compound which has been sold as a designer drug ...
4F-MDMB-BINACA (also known as MDMB-4F-BINACA, [2] 4F-MDMB-BUTINACA or 4F-ADB) is an indazole-based synthetic cannabinoid from the indazole-3-carboxamide family. [3] It should not be confused with the amantadine analogue 4F-ABINACA. It has been used as an active ingredient in synthetic cannabis products and sold as a designer drug since late 2018.
AB-CHMINACA is an indazole-based synthetic cannabinoid.It is a potent agonist of the CB 1 receptor (K i = 0.78 nM) and CB 2 receptor (K i = 0.45 nM) and fully substitutes for Δ 9-THC in rat discrimination studies, while being 16x more potent.
S-444,823 is a drug developed by Shionogi which is a cannabinoid agonist. [1] It was developed as an antipruritic, and has moderate selectivity for the CB 2 subtype, having a CB 2 affinity of 18nM, and 32x selectivity over the CB 1 receptor.