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Severe cutaneous adverse reactions (SCARs) are a group of potentially lethal adverse drug reactions that involve the skin and mucous membranes of various body openings such as the eyes, ears, and inside the nose, mouth, and lips. In more severe cases, SCARs also involves serious damage to internal organs. SCARs includes five syndromes:
Scar sarcoid (also known as "Sarcoidosis in scars") is a cutaneous condition characterized by infiltration and elevation of tattoos and old flat scars due to sarcoidosis. [ 2 ] : 710 Mucosal sarcoidosis is a cutaneous condition characterized by pinhead-sized papules that may be grouped and fused together to form a flat plaque.
Targetoid hemosiderotic hemangioma manifests as a single, tiny, reddish-violaceous to brown targetoid lesion that can grow centrifugally in the acute phase is encircled by a hemorrhagic halo. [3] The halo may vanish in later phases, leaving just a central papule. [4] [5] There have been reports of certain cases without targetoid development. [6]
A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids. [1] Like keloids, they form most often at the sites of pimples, body piercings, cuts and burns. They often contain nerves and blood vessels.
Aplasia cutis congenita (cutis aplasia, congenital absence of skin, congenital scars) Arteriovenous fistula; Benign neonatal hemangiomatosis; Branchial cyst (branchial cleft cyst) Bronchogenic cyst; Capillary hemangioma (infantile hemangioma, nevus maternus, strawberry hemangioma, strawberry nevus) Cavernous venous malformation
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
Rhagades are fissures, cracks, or linear scars in the skin, especially at the angles of the mouth and nose. They tend to form at areas of motion. They tend to form at areas of motion. They can be a result from bacterial infection of skin lesions.
Wound contracture following deep burn injury. Wound contracture is a process that may occur during wound healing when an excess of wound contraction, a normal healing process, leads to physical deformity characterized by skin constriction and functional limitations.