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As frequency increases (and so does resolution), maximum imaging depth decreases. Typically, micro-ultrasound can image tissue of around 3 cm below the skin, and this is more than sufficient for small animals such as mice. The performance of ultrasound imaging is often perceived as to be linked with the experience and skills of the operator.
MRI has the advantages of having very high spatial resolution and is very adept at morphological imaging and functional imaging. MRI does have several disadvantages though. First, MRI has a sensitivity of around 10 −3 mol/L to 10 −5 mol/L, which, compared to other types of imaging, can be very limiting. This problem stems from the fact that ...
Resolution: Medical MRI resolution is typically about 1 mm; the desired resolution of MRM is 100 μm or smaller to 10 μm, comparable with histology. Specimen size: Medical MRI machines are designed so that a patient may fit inside. MRM chambers are usually small, typically less than 1 cm 3 for the imaging of rats, mice and rodents. BrukerBio ...
Two forms of radiographic images are in use in medical imaging. Projection radiography and fluoroscopy, with the latter being useful for catheter guidance. These 2D techniques are still in wide use despite the advance of 3D tomography due to the low cost, high resolution, and depending on the application, lower radiation dosages with 2D technique.
Diffusion imaging is an MRI method that produces in vivo magnetic resonance images of biological tissues sensitized with the local characteristics of molecular diffusion, generally water (but other moieties can also be investigated using MR spectroscopic approaches). [15] MRI can be made sensitive to the motion of molecules.
1977/1978 - Raymond Damadian built the first MRI scanner and achieved the first MRI scan of a healthy human body (1977) with the intent of diagnosing cancer. [4] Additionally, Peter Mansfield develops the echo-planar technique, producing images in seconds and becoming the basis for fast MRIs. [5] 1983 - Introduction of the k-space by D B Twieg [6]
In 2010, an extended FLASH method with highly undersampled radial data encoding and iterative image reconstruction achieved real-time MRI with a temporal resolution of 20 milliseconds (1/50th of a second). [4] [5] Taken together, this latest development corresponds to an acceleration by a factor of 10,000 compared to the MRI situation before ...
Amplified magnetic resonance imaging (aMRI) [1] [2] is an MRI method that is coupled with video magnification processing methods [3] [4] to amplify the subtle spatial variations in MRI scans and to enable better visualization of tissue motion. aMRI can enable better visualization of tissue motion to aid the in vivo assessment of the biomechanical response in pathology.