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Overview of the citric acid cycle. The citric acid cycle—also known as the Krebs cycle, Szent–Györgyi–Krebs cycle, or TCA cycle (tricarboxylic acid cycle) [1] [2] —is a series of biochemical reactions to release the energy stored in nutrients through the oxidation of acetyl-CoA derived from carbohydrates, fats, proteins, and alcohol.
Aerobic respiration requires oxygen (O 2) in order to create ATP. Although carbohydrates , fats and proteins are consumed as reactants , aerobic respiration is the preferred method of pyruvate production in glycolysis , and requires pyruvate be transported the mitochondria in order to be oxidized by the citric acid cycle .
Although physiologic respiration is necessary to sustain cellular respiration and thus life in animals, the processes are distinct: cellular respiration takes place in individual cells of the organism, while physiologic respiration concerns the diffusion and transport of metabolites between the organism and the external environment.
The terms aerobic respiration, anaerobic respiration and fermentation (substrate-level phosphorylation) do not refer to primary nutritional groups, but simply reflect the different use of possible electron acceptors in particular organisms, such as O 2 in aerobic respiration, or nitrate (NO − 3), sulfate (SO 2−
Aerobic respiration proceeds in a series of steps, which also increases efficiency - since glucose is broken down gradually and ATP is produced as needed, less energy is wasted as heat. This strategy results in the waste products H 2 O and CO 2 being formed in different amounts at different phases of respiration.
[1] [2] In this type of respiration, oxygen serves as the terminal electron acceptor for the electron transport chain. [1] Aerobic respiration has the advantage of yielding more energy ( adenosine triphosphate or ATP ) than fermentation or anaerobic respiration , [ 3 ] but obligate aerobes are subject to high levels of oxidative stress .
If more carbon dioxide than usual has been lost by a short period of hyperventilation, respiration will be slowed down or halted until the alveolar partial pressure of carbon dioxide has returned to 5.3 kPa (40 mmHg). It is therefore strictly speaking untrue that the primary function of the respiratory system is to rid the body of carbon ...
In respiratory physiology, the oxygen cascade describes the flow of oxygen from air to mitochondria, where it is consumed in aerobic respiration to release energy. [1] Oxygen flows from areas with high partial pressure of oxygen (PO 2, also known as oxygen tension) to areas of lower PO 2.