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  2. Hypertryptophanemia - Wikipedia

    en.wikipedia.org/wiki/Hypertryptophanemia

    A number of abnormalities and symptoms have been observed with hypertryptophanemia. [citation needed]Musculoskeletal effects include: joint contractures of the elbows and interphalangeal joints of the fingers and thumbs (specifically the distal phalanges), pes planus (fallen arches), an ulnar drift affecting the fingers of both hands (an unusual, yet correctible feature where the fingers slant ...

  3. Tryptophan - Wikipedia

    en.wikipedia.org/wiki/Tryptophan

    Tryptophan ball and stick model spinning. Tryptophan (symbol Trp or W) [3] is an α-amino acid that is used in the biosynthesis of proteins.Tryptophan contains an α-amino group, an α-carboxylic acid group, and a side chain indole, making it a polar molecule with a non-polar aromatic beta carbon substituent.

  4. Pelvic floor dysfunction - Wikipedia

    en.wikipedia.org/wiki/Pelvic_floor_dysfunction

    Overactive bladder can be treated with medications, including those in the class of antimuscarinics and beta 3 agonists. Antimuscarinics are the most commonly used, however, beta 3 agonists can be used for those that are unable to take antimuscarinics due to side effects or other reasons. [4]

  5. Vibegron - Wikipedia

    en.wikipedia.org/wiki/Vibegron

    Vibegron, sold under the brand name Gemtesa, is a medication for the treatment of overactive bladder. [1] [5] [6] Vibegron is a selective beta-3 adrenergic receptor agonist. [1] The most common side effects include headache, urinary tract infection, common cold, diarrhea, nausea, and upper respiratory tract infection. [5]

  6. 5-HT3 antagonist - Wikipedia

    en.wikipedia.org/wiki/5-HT3_antagonist

    There are few side effects related to the use of 5-HT 3 antagonists; the most common are constipation or diarrhea, headache, and dizziness. [28] Unlike antihistamines with antiemetic properties such as cyclizine , 5-HT 3 antagonists do not produce sedation , nor do they cause extrapyramidal effects , as phenothiazines (such as prochlorperazine ...

  7. Eosinophilia–myalgia syndrome - Wikipedia

    en.wikipedia.org/wiki/Eosinophilia–myalgia...

    Eosinophilia–myalgia syndrome is a rare, sometimes fatal neurological condition linked to the ingestion of the dietary supplement L-tryptophan. [1] [2] The risk of developing EMS increases with larger doses of tryptophan and increasing age. [3]

  8. Fenclonine - Wikipedia

    en.wikipedia.org/wiki/Fenclonine

    The effects of serotonin depletion from fenclonine are so drastic that serotonin cannot even be detected immunohistochemically within the first day after administration of a control dose. Tryptophan hydroxylase activity can be detected neither in cell bodies or nerve terminals.

  9. Blue diaper syndrome - Wikipedia

    en.wikipedia.org/wiki/Blue_diaper_syndrome

    It is caused by a defect in tryptophan absorption. Bacterial degradation of unabsorbed tryptophan in the intestine leads to excessive indole production and thus to indicanuria which, on oxidation to indigo blue, causes a peculiar bluish discoloration of the diaper (indoluria). Symptoms typically include digestive disturbances, fever and visual ...