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It can play a role in the metabolic effects of PCOS — like weight gain and a higher risk of diabetes. A poor response to insulin can cause your body to make more. And higher insulin levels might ...
Because of this PCOS effect, metabolic syndrome increases a person's risk of health problems, including heart disease, diabetes and stroke. "As such, women with PCOS are at increased risk of ...
Conditions that cause hormonal imbalances can also increase your risk of insulin resistance. Some of these include PCOS, Cushing’s syndrome, and pregnancy, which can lead to gestational diabetes ...
Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom and not the underlying cause of the disorder.
Increased insulin in the blood stimulates the ovaries to produce more androgens increasing the risk of hyperandrogenism that can interfere with the HPO Axis and result with the pathway mentioned previously. [11] In addition, pregnant women with a history of insulin resistance caused by PCOS have an increased risk of gestational diabetes. [22]
Not all women with PCOS have difficulty becoming pregnant. For those who do, anovulation is a common cause. The mechanism of this anovulation is uncertain, but there is evidence of arrested antral follicle development, which, in turn, may be caused by abnormal interaction of insulin and luteinizing hormone (LH) on granulosa cells.
Why Does PCOS Cause Weight Gain? The body is a complex system and several interconnected mechanisms can make it harder to lose weight when you have PCOS. First, insulin resistance is common in PCOS.
There are a number of risk factors for insulin resistance, including being overweight or obese or having a sedentary lifestyle. [1] Various genetic factors can increase risk, such as a family history of diabetes, and there are some specific medical conditions associated with insulin resistance, such as polycystic ovary syndrome. [1]