Search results
Results from the WOW.Com Content Network
Download as PDF; Printable version; In other projects Wikidata item ... DECIPHER is a software that can be used to decipher and manage biological sequences ...
Name Description Knots [Note 1]Links References trRosettaRNA: trRosettaRNA is an algorithm for automated prediction of RNA 3D structure. It builds the RNA structure by Rosetta energy minimization, with deep learning restraints from a transformer network (RNAformer). trRosettaRNA has been validated in blind tests, including CASP15 and RNA-Puzzles, which suggests that the automated predictions ...
The read alignments are sorted using SAMtools, after which variant callers such as GATK [20] are used to identify differences compared to the reference sequence. The choice of variant calling tool depends heavily on the sequencing technology used, so GATK is often used when working with short reads, while long read sequences require tools like ...
GENSCAN's implementation differs from other programs in multiple ways. A notable difference is the fact that GENSCAN utilizes a genomic sequence model that exclusively focuses double-stranded DNA where genes that are present on both strands are simultaneously analyzed. Also, GENSCAN is capable of analyzing genomes in situations where there are ...
PCAHIER, [17] another binning algorithm developed by the Georgia Institute of Technology., employs n-mer oligonucleotide frequencies as the features and adopts a hierarchical classifier (PCAHIER) for binning short metagenomic fragments. The principal component analysis was used to reduce the high dimensionality of the feature space.
Ab Initio gene prediction is an intrinsic method based on gene content and signal detection. Because of the inherent expense and difficulty in obtaining extrinsic evidence for many genes, it is also necessary to resort to ab initio gene finding, in which the genomic DNA sequence alone is systematically searched for certain tell-tale signs of protein-coding genes.
Genomic browsers can be divided into web-based genomic browsers and stand-alone genomic browsers. The former use information from databases and can be classified into multiple-species (integrate sequence and annotations of multiple organisms and promote cross-species comparative analysis) and species-specific (focus on one organism and the ...
DECIPHER is a web-based resource and database of genomic variation data from analysis of patient DNA. [ 1 ] [ 2 ] [ 3 ] It documents submicroscopic chromosome abnormalities ( microdeletions and duplications ) and pathogenic sequence variants (single nucleotide variants - SNVs, Insertions, Deletions, InDels), from over 25000 patients and maps ...