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UniProtKB/Swiss-Prot is a manually annotated, non-redundant protein sequence database. It combines information extracted from scientific literature and biocurator -evaluated computational analysis. The aim of UniProtKB/Swiss-Prot is to provide all known relevant information about a particular protein.
Protein sequence databases Swiss-Prot: Swiss Institute of Bioinformatics: protein knowledgebase Protein sequence databases Protein Data Bank: Protein DataBank in Europe (PDBe), [18] ProteinDatabank in Japan (PDBj), [19] Research Collaboratory for Structural Bioinformatics (RCSB) [20] (PDB) Protein structure databases Structural Classification ...
The institute was originally created to provide a framework for stable long-term funding for both the Swiss-Prot database and the Swiss EMBnet node. Swiss-Prot in particular went through a major funding crisis in 1996, [1] which led the leaders of the five research groups active in bioinformatics in Geneva and Lausanne, Ron Appel, Amos Bairoch, Philipp Bucher, Victor Jongeneel and Manuel ...
In 2002, PIR – along with its international partners, the European Bioinformatics Institute and the Swiss Institute of Bioinformatics – were awarded a grant from NIH to create UniProt, a single worldwide database of protein sequence and function, by unifying the Protein Information Resource-Protein Sequence Database, Swiss-Prot, and TrEMBL ...
The UniProt database is an example of a protein sequence database. As of 2013 it contained over 40 million sequences and is growing at an exponential rate. [ 1 ] Historically, sequences were published in paper form, but as the number of sequences grew, this storage method became unsustainable.
Also, includes protein pathways and gene sequences including other tools. SCOP the Structural Classification of Proteins a detailed and comprehensive description of the structural and evolutionary relationships between all proteins whose structure is known. SWISS-MODEL Repository a database of annotated protein models calculated by homology ...
Apweiler has been working on the Swiss-Prot [13] protein sequence database since 1987, and in 1994 he became leader of the Swiss-Prot group. He has been joint head of the Protein and Nucleotide Data (PANDA) Group since 2007.
PROSITE is a protein database. [1] [2] It consists of entries describing the protein families, domains and functional sites as well as amino acid patterns and profiles in them.. These are manually curated by a team of the Swiss Institute of Bioinformatics and tightly integrated into Swiss-Prot protein annotati