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Dementia, however, can present early in its disease course with depressive symptoms, meaning that this association could actually be reflecting that dementia causes late life depression. [23] Studies that have directly tried to determine whether depression is an independent risk factor for dementia have led to inconclusive results.
Malaise is a non-specific symptom and can be present in the slightest ailment, such as an emotion (causing fainting, a vasovagal response) or hunger (light hypoglycemia [2]), to the most serious conditions (cancer, stroke, heart attack, internal bleeding, etc.).
Management of ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) focuses on symptoms management, as no treatments that address the root cause of the illness are available. [ 1 ] : 29 Pacing, or regulating one's activities to avoid triggering worse symptoms, is the most common management strategy for post-exertional malaise .
ME/CFS causes debilitating fatigue, sleep problems, and post-exertional malaise (PEM, overall symptoms getting worse after mild activity). In addition, cognitive issues, orthostatic intolerance (dizziness or nausea when upright) or other physical symptoms may be present (see also § Diagnostic criteria ).
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Post-exertional malaise; Other names: Post-exertional symptom exacerbation (PESE) Postexertional malaise (PEM) Post-exertional neuroimmune exhaustion (PENE) Chart of physical, cognitive, and emotional activities that may trigger PEM: Symptoms: Worsening of symptoms after ordinary activity: Causes: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Fluid builup in the lower legs, feet and hands—also known as pedal edema— occurs because the heart’s ability to pump blood is too weak, which causes the blood to settle and accumulate in tissue.
Overall, our findings suggest that more people over 70 years of age should be considered for statin treatment.” — Borislava Mihaylova, DPhil “Cardiovascular disease remains a leading cause ...