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Short tandem repeat (STR) analysis is a common molecular biology method used to compare allele repeats at specific loci in DNA between two or more samples. A short tandem repeat is a microsatellite with repeat units that are 2 to 7 base pairs in length, with the number of repeats varying among individuals, making STRs effective for human ...
For example, experiments in which each condition takes only a few minutes, whereas the training to complete the tasks take as much, if not more time. Longitudinal analysis—Repeated measure designs allow researchers to monitor how participants change over time, both long- and short-term situations.
In engineering, science, and statistics, replication is the process of repeating a study or experiment under the same or similar conditions. It is a crucial step to test the original claim and confirm or reject the accuracy of results as well as for identifying and correcting the flaws in the original experiment. [1]
A less-than-perfect test–retest reliability causes test–retest variability. Such variability can be caused by, for example, intra-individual variability and inter-observer variability . A measurement may be said to be repeatable when this variation is smaller than a predetermined acceptance criterion.
Analysis of the genotypes in the samples usually involves sizing of the amplification products by gel electrophoresis. Analysis of smaller VNTR segments known as short tandem repeats (or STRs) is the basis for DNA fingerprinting databases such as CODIS. Asymmetric PCR preferentially amplifies one strand of a double-stranded DNA target.
The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of sequential analysis, a field that was pioneered [13] by Abraham Wald in the context of sequential tests of statistical hypotheses. [14]
A "VNTR" is a "variable-number tandem repeat". This method is well known in forensic science since it is the basis of DNA fingerprinting in humans. When applied to bacteria, it contributes to forensic microbiology through which the source of a particular strain might eventually be traced back, making it a useful technique for outbreak surveillance.
Analysis of covariance (ANCOVA) is a general linear model that blends ANOVA and regression. ANCOVA evaluates whether the means of a dependent variable (DV) are equal across levels of one or more categorical independent variables (IV) and across one or more continuous variables.