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Buruli ulcer (/ b ə ˈ r uː l i /) [2] is an infectious disease characterized by the development of painless open wounds. The disease is limited to certain areas of the world, with most cases occurring in Sub-Saharan Africa and Australia.
The Global Buruli Ulcer Initiative (GBUI) is a World Health Organization (WHO) initiative to coordinate global efforts to control Buruli ulcer, [1] an infectious disease characterized by the development of painless open wounds. [2]
The prevalence of Buruli ulcer is unknown. [18] The risk of mortality is low, although secondary infections can be lethal. [35] Morbidity takes the form of deformity, disability, and skin lesions, which can be prevented through early treatment with antibiotics and surgery. [35] It is found in Africa, Asia, Australia, [36] and Latin America. [37]
Buruli ulcer is an infectious disease characterized by the development of painless open wounds. The disease largely occurs in sub-Saharan Africa and Australia, generally in rural areas near slow-moving or stagnant water. The first sign of infection is a small painless nodule or area of swelling, typically on the arms or legs.
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Seleoane’s only remaining family is her estranged brother in Britain and long-lost relatives in South Africa, News 24 reported. Her remains were sent to South Africa where she was buried.
The disease often goes untreated because of the scarcity of medical treatment in the countries in which it is found. In addition, the painless genital ulcers can be mistaken for syphilis. [5] The ulcers ultimately progress to destruction of internal and external tissue, with extensive leakage of mucus and blood from the highly vascular lesions.
Once developed, the ulcer may become chronic and stable, but also it can run a destructive course with deep tissue invasion, osteitis, and risk of amputation. Unlike Buruli ulcer, tropical ulcers are very painful. [4] Lesions begin with inflammatory papules that progress into vesicles and rupture with the formation of an ulcer. [1]