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  2. Acid dissociation constant - Wikipedia

    en.wikipedia.org/wiki/Acid_dissociation_constant

    Because the relationship pK b = pK w − pK a holds only in aqueous solutions (though analogous relationships apply for other amphoteric solvents), subdisciplines of chemistry like organic chemistry that usually deal with nonaqueous solutions generally do not use pK b as a measure of basicity. Instead, the pK a of the conjugate acid, denoted by ...

  3. Acid strength - Wikipedia

    en.wikipedia.org/wiki/Acid_strength

    Acid strength is the tendency of an acid, symbolised by the chemical formula, to dissociate into a proton, +, and an anion, .The dissociation or ionization of a strong acid in solution is effectively complete, except in its most concentrated solutions.

  4. Potassium hydrogen phthalate - Wikipedia

    en.wikipedia.org/wiki/Potassium_hydrogen_phthalate

    The pKa of KHP is 5.4, so its pH buffering range would be 4.4 to 6.4; however, due to the presence of the second acidic group that bears the potassium ion, the first pKa also contributes to the buffering range well below pH 4.0, which is why KHP is a good choice for use as a reference standard for pH 4.00. [8] [9]

  5. Henderson–Hasselbalch equation - Wikipedia

    en.wikipedia.org/wiki/Henderson–Hasselbalch...

    In chemistry and biochemistry, the Henderson–Hasselbalch equation = + ⁡ ([] []) relates the pH of a chemical solution of a weak acid to the numerical value of the acid dissociation constant, K a, of acid and the ratio of the concentrations, [] [] of the acid and its conjugate base in an equilibrium.

  6. Dissociation (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Dissociation_(chemistry)

    Dissociation in chemistry is a general process in which molecules (or ionic compounds such as salts, or complexes) separate or split into other things such as atoms, ions, or radicals, usually in a reversible manner.

  7. Methyl orange - Wikipedia

    en.wikipedia.org/wiki/Methyl_orange

    Because it changes color at the pK a of a mid strength acid, it is usually used in titration of strong acids in weak bases that reach the equivalence point at a pH of 3.1-4.4. [3] Unlike a universal indicator , methyl orange does not have a full spectrum of color change, but it has a sharp end point.

  8. Deprotonation - Wikipedia

    en.wikipedia.org/wiki/Deprotonation

    The solvent used can also assist in the stabilization of the negative charge on a conjugated base. Bases used to deprotonate depend on the p K a of the compound. When the compound is not particularly acidic , and, as such, the molecule does not give up its proton easily, a base stronger than the commonly known hydroxides is required.

  9. Equilibrium constant - Wikipedia

    en.wikipedia.org/wiki/Equilibrium_constant

    For bases, the base association constant, pK b is used. For any given acid or base the two constants are related by pK a + pK b = pK w, so pK a can always be used in calculations. On the other hand, stability constants for metal complexes, and binding constants for host–guest complexes are generally expressed as association constants. When ...