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To date, most sleep deprivation studies have focused on acute sleep deprivation, suggesting that acute sleep deprivation can cause significant damage to cognitive, emotional, and physical functions and brain mechanisms. [11] Few studies have compared the effects of acute total sleep deprivation and chronic partial sleep restriction. [8]
Sleep deprivation may additionally affect memory by reducing the proliferation of cells in the hippocampus. [51] Sleep deprivation has also been associated with decreased overall membrane excitability of neurons in the brain. Activation of these membranes is critical for the formation of memories. [52]
Animals studies showed that sleep deprivation prior to a brain injury might have healthy effects. Five days of complete sleep deprivation in rats before the traumatic brain injury, acted as protection against ischemic injury [21] and a habitual deceased in total amount of sleep time before TBI reduced the severity. [22]
Sleep deprivation is common and sometimes even necessary in modern societies because of occupational and domestic reasons like round-the-clock service, security or media coverage, cross-time-zone projects etc. This makes understanding the effects of sleep deprivation very important. Many studies have been done from the early 1900s to document ...
Sleep disturbances often occur before the onset of psychosis. Sleep deprivation can also produce hallucinations, delusions and depression. [26] A 2019 study investigated the three above-mentioned sleep disturbances in schizophrenia-spectrum (SCZ) and bipolar (BP) disorders in 617 SCZ individuals, 440 BP individuals, and 173 healthy controls (HC).
The response rate to sleep deprivation is generally agreed to be approximately 40-60%. A 2017 meta-analysis of 66 sleep studies with partial or total sleep deprivation in the treatment of depression found that the overall response rate (immediate relief of symptoms) to total sleep deprivation was 50.4% of individuals, and the response rate to partial sleep deprivation was 53.1% [3] In 2009, a ...
Shows convergent validity with other symptom scales such as ESS and Karolinska Sleepiness Scale, [6] prediction of performance after sleep deprivation [4] Discriminative validity: Adequate: Studies do not report AUCs, some mention overlap between sleepiness, physical tiredness, and depression [4] Validity generalization: Good
A large sleep debt may lead to mental or physical fatigue, and can adversely affect one's mood, energy, and ability to think clearly. There are two kinds of sleep debt: the result of partial sleep deprivation, and of total sleep deprivation. Partial sleep deprivation occurs when a person or a lab animal sleeps too little for several days or ...