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p16 (also known as p16 INK4a, cyclin-dependent kinase inhibitor 2A, CDKN2A, multiple tumor suppressor 1 and numerous other synonyms), is a protein that slows cell division by slowing the progression of the cell cycle from the G1 phase to the S phase, thereby acting as a tumor suppressor. It is encoded by the CDKN2A gene.
SFGate is a news website based in San Francisco, California, covering news, culture, travel, food, politics and sports in the San Francisco Bay Area, Hawaii and California. The site, owned by Hearst Newspapers , reaches approximately 25 million to 30 million unique readers a month, making it the second most popular news site in California after ...
The North Bay is a subregion of the San Francisco Bay Area, in California, United States. The largest city is Santa Rosa , which is the fifth-largest city in the Bay Area. It is the location of the Napa and Sonoma wine regions , and is the least populous and least urbanized part of the Bay Area.
All vehicular crossings of the San Francisco Bay land in the counties comprising the East Bay. Interstate highways in the East Bay include Interstates 80 , 580 , 680 , 880 , 980 , and 238 . California State Routes 24 , 4 , 13 , 92 , 160 , 242 , 84 , and Richmond Parkway are limited access highways for at least part of their lengths in the area.
In the early morning of April 18, 1906, a large earthquake with an epicenter near the city of San Francisco hit the region. [40] Immediate casualty estimates by the U.S. Army's relief operations were 498 deaths in San Francisco, 64 deaths in Santa Rosa, and 102 in or near San Jose, for a total of about 700.
The San Francisco Peninsula is a peninsula in the San Francisco Bay Area that separates San Francisco Bay from the Pacific Ocean. On its northern tip is the City and County of San Francisco . Its southern base is Los Altos and Mountain View , in Santa Clara County , south of Palo Alto and north of Sunnyvale .
This is a combined list of all national, state, and local landmarks and historic places in San Francisco, California. Some locations appear on multiple lists. Some locations appear on multiple lists. National
Bay Area Rapid Transit (BART) is a rapid transit system serving the San Francisco Bay Area in California.BART serves 50 stations along six routes and 131 miles (211 kilometers) of track, including eBART, a 9-mile (14 km) spur line running to Antioch, and Oakland Airport Connector, a 3-mile (4.8 km) automated guideway transit line serving Oakland International Airport.
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