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The Human Cell Atlas is a global project to describe all cell types in the human body. [1] The initiative was announced by a consortium after its inaugural meeting in London in October 2016, which established the first phase of the project.
The Human Cell Atlas project, which started in 2016, had as one of its goals to "catalog all cell types (for example, immune cells or brain cells) and sub-types in the human body". [13] By 2018, the Human Cell Atlas description based the project on the assumption that "our characterization of the hundreds of types and subtypes of cells in the ...
A cell type is a classification used to identify cells that share morphological or phenotypical features. [1] A multicellular organism may contain cells of a number of widely differing and specialized cell types, such as muscle cells and skin cells , that differ both in appearance and function yet have identical genomic sequences .
Among the products of the program is the Azimuth reference datasets for single-cell RNA seq data [2] [3] and the ASCT+B Reporter, a visualization tool for anatomical structures, cell types and biomarkers. [4] [5] Millitomes are used to create uniformly sized tissue blocks that match the shape and size of organs from HuBMAP's 3D Reference Object ...
The Human Protein Atlas (HPA) is a Swedish-based program started in 2003 with the aim to map all the human proteins in cells, tissues and organs using integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics and systems biology.
The cell on the left is going through mitosis and its chromosomes have condensed. Cell nucleus: A cell's information center, the cell nucleus is the most conspicuous organelle found in a eukaryotic cell. It houses the cell's chromosomes, and is the place where almost all DNA replication and RNA synthesis (transcription) occur.
The Expression Atlas allows searches by gene, splice variant, protein attribute, disease, treatment or organism part (cell types/tissues). Individual genes or gene sets can be searched for. All datasets in Expression Atlas have its metadata manually curated and its data analysed through standardised analysis pipelines.
The Cell Ontology is an ontology that aims at capturing the diversity of cell types in animals. [1] It is part of the Open Biomedical and Biological Ontologies (OBO) Foundry. [2] The Cell Ontology identifiers and organizational structure are used to annotate data at the level of cell types, for example in single-cell RNA-seq studies. [3]