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Phenylbiguanide (PBG) is a 5-HT3 agonist used to study the role of 5-HT3 receptors in the central nervous system. [1] It has been found to trigger dopamine release in the nucleus accumbens of rats. [ 2 ]
The Palace of Truth is a three-act blank verse "Fairy Comedy" by the English dramatist W. S. Gilbert. First produced at the Haymarket Theatre in London on 19 November 1870, the plot was adapted in significant part from Madame de Genlis 's fairy story Le Palais de Vérite .
The mechanism of action of biguanides is not fully understood, and many mechanisms have been proposed for metformin. [citation needed]Biguanides do not affect the output of insulin, unlike other hypoglycemic agents such as sulfonylureas and meglitinides.
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Benzothiophene.. The substituted benzothiophenes are a class of chemical compounds based on benzothiophene. [1] [2] They are closely related to the substituted benzofurans, substituted tryptamines, and to other chemical groups such as the substituted benzodioxoles (or methylenedioxy phenyl compounds).
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It acts as a serotonin 5-HT 2A receptor agonist, serotonin 5-HT 2B receptor antagonist, and also interacts with other serotonin receptors, such as the serotonin 5-HT 1F receptor (agonist), 5-HT 2C receptor (very weak partial agonist or antagonist), and 5-HT 6 receptor (agonist).