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Human Cell Atlas; Content; Description: The Human Cell Atlas is a global consortium that is creating detailed maps of the cells in the human body to transform understanding of health and disease. Organisms: Human: Contact; Primary citation: Regev, Aviv; et al. (Human Cell Atlas Organizing Committee) (2018). "The Human Cell Atlas White Paper".
Individual cells within a morphogenetic field in an embryo are flexible: thus, cells in a cardiac field can be redirected via cell-to-cell signaling to replace damaged or missing cells. [6] The Imaginal disc in larvae is an example of a discrete morphogenetic field region of cells in an insect embryo. [7]
Levels of selection (evolution II) Vulnerabilities to disease can result when selection has opposing effects at different levels (e.g. genetic elements, cells, organisms, kin and other levels). Phylogeny (evolution II) Tracing phylogenetic relationships for species, populations, traits or pathogens can provide insights into health and disease ...
In utero development and malformations were correlated in severity. [14] Freiston and Galis look at the development of ribs, digits, and mammalian asymmetry. They argue that this construction is relevant for the study of disease, the consistency in evolution of body plans, and understanding of developmental constraints. [15]
Live cells were stained with DiI (red) or DiO (green). The red cells were genetically altered and express higher levels of E-cadherin than the green cells. The mixed culture forms large multi-cellular aggregates. At a tissue level, ignoring the means of control, morphogenesis arises because of cellular proliferation and motility. [9]
Recent studies have shown the importance in non-coding RNA's ability to regulate cell differentiation and organismal development. There are many types of non-coding RNA that are present and play a role in differentiating stem cells. There are many non-coding RNAs responsible for differentiating cells for human brain and muscle development.
The development of plants involves similar processes to that of animals. However, plant cells are mostly immotile so morphogenesis is achieved by differential growth, without cell movements. Also, the inductive signals and the genes involved are different from those that control animal development.
During gastrulation, some of the cells migrating inward to form the endoderm form an additional layer between the endoderm and the ectoderm. A theory suggests that this key innovation evolved hundreds of millions of years ago and led to the evolution of nearly all large, complex animals. The formation of a mesoderm led to the formation of a ...