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  2. Body surface area - Wikipedia

    en.wikipedia.org/wiki/Body_surface_area

    There was an average BSA of 1.73 m 2 for 3,000 cancer patients from 1990 to 1998 in a European Organisation for Research and Treatment of Cancer (EORTC) database. [19] During 2005 there was an average BSA of 1.79 m 2 for 3,613 adult cancer patients in the UK. Among them the average BSA for men was 1.91 m 2 and for women was 1.71 m 2. [20]

  3. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...

  4. Volume of distribution - Wikipedia

    en.wikipedia.org/wiki/Volume_of_distribution

    Therefore, the dose required to give a certain plasma concentration can be determined if the V D for that drug is known. The V D is not a physiological value; it is more a reflection of how a drug will distribute throughout the body depending on several physicochemical properties, e.g. solubility, charge, size, etc.

  5. Roentgen equivalent man - Wikipedia

    en.wikipedia.org/wiki/Roentgen_equivalent_man

    The deterministic effects that can lead to acute radiation syndrome only occur in the case of high doses (> ~10 rad or > 0.1 Gy) and high dose rates (> ~10 rad/h or > 0.1 Gy/h). A model of deterministic risk would require different weighting factors (not yet established) than are used in the calculation of equivalent and effective dose.

  6. Coefficient of determination - Wikipedia

    en.wikipedia.org/wiki/Coefficient_of_determination

    Ordinary least squares regression of Okun's law.Since the regression line does not miss any of the points by very much, the R 2 of the regression is relatively high.. In statistics, the coefficient of determination, denoted R 2 or r 2 and pronounced "R squared", is the proportion of the variation in the dependent variable that is predictable from the independent variable(s).

  7. Glomerular filtration rate - Wikipedia

    en.wikipedia.org/wiki/Glomerular_filtration_rate

    The normal range of GFR, adjusted for body surface area, is 100–130 average 125 mL/min/1.73m 2 in men and 90–120 ml/min/1.73m 2 in women younger than the age of 40. In children, GFR measured by inulin clearance is 110 mL/min/1.73 m 2 until 2 years of age in both sexes, and then it progressively decreases. After age 40, GFR decreases ...

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    Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!

  9. Plateau principle - Wikipedia

    en.wikipedia.org/wiki/Plateau_Principle

    The blood plasma concentration of vitamin C or ascorbic acid as a function of dose attains a plateau with a half-life of about 2 weeks. [10] Bioavailability of vitamin C is highest at dosages below 200 mg per day. Above 500 mg, nearly all of excess vitamin C is excreted through urine.