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Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [8] [9] It may also be used for hiccups and muscle spasms near the end of life, [9] and off-label to treat alcohol use disorder [10] [11] or opioid withdrawal symptoms. [12]
The recommended dosage of Benadryl tablets for adults is 1 to 2 tablets every 4 to 6 hours, [1] and only 1 tablet every 4 to 6 hours for children under the age of 12. [2]The Benadryl challenge is an internet challenge that emerged in 2020, revolving around the deliberate consumption, excessive use and overdose of the antihistamine medicine diphenhydramine (commonly sold in the United States ...
Solid Documents, the makers of Solid PDF Creator, launched the product in 2006 and have released several version updates since then including 2.0 in 2007. [5] The latest product enhancement, new to version 7, allows for the conversion of Windows-based documents into PDF/A documents in compliance with ISO 19005-1 standards for long-term preservation and archival purposes. [6]
The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose.It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. [1]
Influenza vaccines contain 2.5 μg of polysorbate 80 per dose. [10] Polysorbate 80 is found in many vaccines used in the United States, [11] including the Janssen COVID-19 vaccine. [12] It is used in the culture of Mycobacterium tuberculosis in Middlebrook 7H9 broth. It is also used as an emulsifier in the estrogen-regulating drug Estrasorb. [13]
Dextropropoxyphene [5] is an analgesic in the opioid category, patented in 1955 [6] and manufactured by Eli Lilly and Company.It is an optical isomer of levopropoxyphene.It is intended to treat mild pain and also has antitussive (cough suppressant) and local anaesthetic effects.
Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage).
Drug content uniformity is a requirement for all dosage forms, particularly those containing low dose highly potent drugs. To uniquely meet this requirement, thin film formulations contain uniform dispersions of drug throughout the whole manufacturing process. [ 5 ]
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