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This causes the skin to lose moisture and it may crack and peel. Bathing or hand washing too frequently, especially if one is using harsh soaps , can contribute to xeroderma. Xeroderma can be caused by a deficiency of vitamin A , vitamin D , zinc , systemic illness , severe sunburn , or some medication . [ 4 ]
Scale forms on the skin surface in various disease settings, and is the result of abnormal desquamation. In pathologic desquamation, such as that seen in X-linked ichthyosis, the stratum corneum becomes thicker (hyperkeratosis), imparting a "dry" or scaly appearance to the skin, and instead of detaching as single cells, corneocytes are shed in clusters, which forms visible scales. [2]
Atopic dermatitis (or eczema) is the most common inflammatory skin disease. Skin may slough in a peeling fashion. Contact dermatitis arises from contact with a skin irritant. The ensuing irritation can cause sores and skin sloughing. and Seborrheic dermatitis which is associated with skin shedding through dandruff.
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“Keratosis pilaris, which can be referred to as ‘chicken skin’ or in some cases, ‘strawberry legs,’ is a condition caused by keratin buildup—a protein that helps form hair, nails, and ...
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Keratolysis exfoliativa normally appears during warm weather. Due to excessive sweating and friction, in for example athletic shoes, the skin can start to exfoliate. Other factors that can cause exfoliation are detergents and solvents. Another very common cause has been reported from salt water fishermen, who often suffer from these symptoms.
Chronic scratching of lesions can cause thickening or lichenification of the skin or prurigo nodularis (generalized nodules that are severely itchy). [ 33 ] Another factor in the barrier failure and immunological dysregulation in people with atopic dermatitis may be due to decreases in tight junction protein Claudin-1 .