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The question of how schizophrenia could be primarily genetically influenced, given that people with schizophrenia have lower fertility rates, is a paradox. It is expected that genetic variants that increase the risk of schizophrenia would be selected against, due to their negative effects on reproductive fitness .
Paranoia is distinct from phobias, which also involve irrational fear, but usually no blame. Making false accusations and the general distrust of other people also frequently accompany paranoia. [2] For example, a paranoid person might believe an incident was intentional when most people would view it as an accident or coincidence.
Schizotypal personality disorder (StPD or SPD), also known as schizotypal disorder, is a cluster A personality disorder. [4] [5] The Diagnostic and Statistical Manual of Mental Disorders (DSM) describes the disorder specifically as a personality disorder characterized by thought disorder, paranoia, a characteristic form of social anxiety, derealization, transient psychosis, and unconventional ...
The delusions do not interfere with general logical reasoning (although within the delusional system the logic is perverted) and there is usually no general disturbance of behavior. If disturbed behavior does occur, it is directly related to the delusional beliefs. The individual experiences a heightened sense of self-reference.
Thus, researchers hypothesize schizophrenia to be a homozygotic condition, and that asymptomatic heterozygotes are favored over average people. [17] Individuals with active symptoms of schizophrenia are more likely to seclude themselves from others, avoiding circumstances that may lead to excess amounts of stress or anxiety.
Dementia praecox was reconstituted as schizophrenia, paranoia was renamed as delusional disorder and manic-depressive insanity as bipolar disorder (epilepsy was transferred from psychiatry to neurology). The 'mental symptoms' included under the concept schizophrenia are real enough, affect people, and will always need understanding and treatment.
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