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If TB bacteria gain entry to the blood stream from an area of damaged tissue, they can spread throughout the body and set up many foci of infection, all appearing as tiny, white tubercles in the tissues. [96] This severe form of TB disease, most common in young children and those with HIV, is called miliary tuberculosis. [97]
In addition, between 1851 and 1910, around four million died from TB in England and Wales – more than one third of those aged 15 to 34 and half of those aged 20 to 24 died from TB. [62] By the late 19th century, 70–90% of the urban populations of Europe and North America were infected with the Mycobacterium tuberculosis , and about 80% of ...
Phantom Plague: How Tuberculosis Shaped our History is a 2022 non-fiction book about the history of tuberculosis by health journalist Vidya Krishnan. [1] [2]It covers the history of tuberculosis through the 19th, 20th, and early 21st centuries, from early understandings of the disease to modern public health and pharmaceutical interventions.
Also, the IGRA is more specific to TB rather than other types of mycobacterial infections and is unlikely to be positive as a result of having BCG vaccine in the past, a vaccine that protects against TB. And this is a pretty useful feature of IGRAs, since BCG vaccine is given to many children around the world to prevent disseminated TB.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
[21] [22] According to the World Health Organization, approximately 10 million new TB infections occur every year, and 1.5 million people die from it each year – making it the world's top infectious killer (before COVID-19 pandemic). [21] However, there is a lack of sources which describe major TB epidemics with definite time spans and death ...
As of 2018, the World Health Organization estimated that 25% of the world's population was infected with the latent form of the disease. In its active form, it is one of the top 10 causes of death worldwide. [1] This bibliography is of non-fiction works about TB in human beings. It covers general works, key scientific papers, treatment methods ...
Children have special needs both in preventing and treating tuberculosis. Tuberculosis is one of India's major public health problems. According to World Health Organization estimates, India has the world's largest tuberculosis epidemic. [5] In 2020, India accounted for 26% of the incident TB cases across the globe.