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Lipoproteins released from treatment of Treponema pallidum infections are believed to induce the Jarisch–Herxheimer reaction. [3] The Herxheimer reaction has shown an increase in inflammatory cytokines during the period of exacerbation, including tumor necrosis factor alpha , interleukin-6 and interleukin-8 .
[1] [2] [3] In the elderly, xerosis, is the most common cause for an itch due to the degradation of the skin barrier over time. [4] However, the cause of senile pruritus is not clearly known. [5] Diagnosis is based on an elimination criteria during a full body examination that can be done by either a dermatologist or non-dermatologist physician ...
A case of hidradenitis suppurativa Hidradenitis suppurativa can take the form of growths on the skin that are extremely painful and debilitating.. Hidradenitis suppurativa (HS), sometimes known as acne inversa or Verneuil's disease, is a long-term dermatological condition characterized by the occurrence of inflamed and swollen lumps.
Canakinumab, an anti-interleukin-1-beta monoclonal antibody, has likewise been shown to be effective in controlling and preventing flare-ups in patients with colchicine-resistant FMF and in two additional autoinflammatory recurrent fever syndromes: mevolonate kinase deficiency (hyper-immunoglobulin D syndrome, or HIDS) and tumor necrosis factor ...
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
Treatment involves avoiding things that make the condition worse, enhancing the skin barrier through skin care and treating the underlying skin inflammation. Moisturising creams are used to make the skin less dry and prevent AD flare-ups. Anti-inflammatory corticosteroid creams are used to control flares-ups. [3]
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Flare, a redness in the surrounding area due to arteriolar dilation mediated by axon reflex. [1] [2] [3] Wheal, caused by exudation of extracellular fluid from capillaries and venules. [1] [2] [3] The red spot emerges within 15 seconds. [4] Flare can take up to 45 seconds to begin. [4] Wheal can take up to 3 minutes to begin. [4] [5]