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Maritime drug trafficking in Latin America is the primary mean of transportation of illegal drugs produced in this region to global consumer markets. Cocaine is the primary illegal drug smuggled through maritime routes because all of its cultivation and production is settled in the Andean region of South America. [1] [2] The smuggling of drugs ...
The coca cultivation is concentrated in the Andes of South America, particularly in Colombia, Peru and Bolivia; this is the world's only source region for coca. [1] Drug consumption in Latin America remains relatively low, but cocaine in particular has increased in recent years in countries along the major smuggling routes. [1]
Cocaine stimulates the mesolimbic pathway in the brain. [15] Mental effects may include an intense feeling of happiness, sexual arousal, loss of contact with reality, or agitation. [12] Physical effects may include a fast heart rate, sweating, and dilated pupils. [12] High doses can result in high blood pressure or high body temperature. [16]
Two studies [18] [19] have shown that an increase in dendritic spine density due to cocaine exposure facilitates behavioral sensitization, while two other studies [20] [21] produce contradicting evidence. In response to drugs of abuse, structural changes can be observed in the size of neurons [22] and the shape and number of the synapses ...
Cocaine increases alertness, feelings of well-being, euphoria, energy, sociability, and sexuality. The former are some of the desired effects of cocaine intoxication. Not having the normal use of mental faculties by reason of the introduction of cocaine is defined drug intoxication by the laws in America, Europe, and most of the rest of the World, and it is a serious crime in specific contexts ...
In the United States, past year cocaine users in 2019 was 5.5 million for people aged 12 or older. When broken into age groups, ages 12–17 had 97,000 users; ages 18–25 had 1.8 million users and ages 26 or older had 3.6 million users. [10] Past year cocaine users with a cocaine use disorder in 2019 was 1 million for people aged 12 or older.
Both substance use and alcohol can cause both long-term and short-term memory loss, resulting in blackouts. The most commonly used group of prescription drugs which can produce amnesia are benzodiazepines, especially if combined with alcohol, however, in limited quantities, triazolam (Halcion) is not associated with amnesia or memory impairment ...
An implicit premise in neuropsychopharmacology with regard to the psychological aspects is that all states of mind, including both normal and drug-induced altered states, and diseases involving mental or cognitive dysfunction, have a neurochemical basis at the fundamental level, and certain circuit pathways in the central nervous system at a higher level.