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  2. AL amyloidosis - Wikipedia

    en.wikipedia.org/wiki/AL_amyloidosis

    Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis. [1] The disease is caused when a person's antibody-producing cells do not function properly and produce abnormal protein fibers made of components of antibodies called light chains. These light chains come together to form ...

  3. Amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Amyloidosis

    Treatment depends on the type of amyloidosis that is present. Treatment with high dose melphalan, a chemotherapy agent, followed by stem cell transplantation has shown promise in early studies and is recommended for stage I and II AL amyloidosis. [26] However, only 20–25% of people are eligible for stem cell transplant.

  4. Cerebral amyloid angiopathy - Wikipedia

    en.wikipedia.org/wiki/Cerebral_amyloid_angiopathy

    CAA is associated with brain hemorrhages, particularly microhemorrhages.The accumulation of amyloid beta peptide deposits in the blood vessel walls results in damage of the blood vessels and hindrance of normal blood flow, making blood vessels more prone to bleeding [10] Since CAA can be caused by the same amyloid protein that is associated with Alzheimer's dementia, brain bleeds [11] are more ...

  5. LECT2 amyloidosis - Wikipedia

    en.wikipedia.org/wiki/Lect2_amyloidosis

    LECT2 Amyloidosis (ALECT2) is a form of amyloidosis caused by the LECT2 protein. It was found to be the third most common (~3% of total) cause of amyloidosis in a set of more than 4,000 individuals studied at the Mayo Clinic; the first and second most common forms the disorder were AL amyloidosis and AA amyloidosis, respectively.

  6. Dopamine treatment destroys beta-amyloid plaques in ... - AOL

    www.aol.com/lifestyle/dopamine-treatment...

    Researchers say the hormone dopamine may be used as a treatment for Alzheimer's disease as it stimulates the ... One of the hallmarks of Alzheimer’s disease are beta-amyloid plaques in the brain.

  7. Anti-amyloid drugs - Wikipedia

    en.wikipedia.org/wiki/Anti-amyloid_drugs

    Aducanumab, sold under the brand name Aduhelm, is a monoclonal antibody designed to treat Alzheimer's disease. It is a monoclonal antibody that targets aggregated forms (plaque) of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup. [10] It was developed by Biogen and Eisai. [11] Aducanumab is given via intravenous infusion. [5] Aducanumab was ...

  8. Amyloid plaques - Wikipedia

    en.wikipedia.org/wiki/Amyloid_plaques

    Two amyloid plaques from the brain of a patient with Alzheimer's disease. In this photomicrograph , neurites are darkly stained with the Naoumenko-Feigin silver method, and the pink elements (including the plaque cores) are stained with the periodic acid-Schiff (PAS) counterstain.

  9. Light chain deposition disease - Wikipedia

    en.wikipedia.org/wiki/Light_chain_deposition_disease

    Light chain deposition disease can affect any organ. [3] Renal involvement is always present and can be identified by microscopic hematuria and proteinuria.Due to the gradual buildup of light chains from plasma filtration, renal function rapidly declines in the majority of patients with LCDD as either acute tubulointerstitial nephritis or rapidly progressing glomerulonephritis.

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