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Interleukin-2 (IL-2) is an interleukin, which is a type of cytokine signaling molecule forming part of the immune system. It is a 15.5–16 kDa protein [ 5 ] that regulates the activities of white blood cells (leukocytes, often lymphocytes ) that are responsible for immunity.
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Interleukin 2 combined with diphtheria toxin which binds to the interleukin receptor on immune cells and introduces the diphtheria toxin into the cell. Cutaneous T cell lymphoma and peripheral T cell lymphoma (orphan).
Drug Mechanism of action Indications Toxicity; Abciximab: A monoclonal antibody that binds to the glycoprotein receptor IIb/IIIa on activated platelets, preventing aggregation Acute coronary syndromes, percutaneous transluminal coronary angioplasty Bleeding, thrombocytopenia: Anakinra (Kineret) A recombinant version of the Interleukin 1 ...
ATC code L04 Immunosuppressants is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Interleukin 6 (IL6), also referred to as B-cell stimulatory factor-2 (BSF-2) and interferon beta-2, is a cytokine involved in a wide variety of biological functions. [20] It plays an essential role in the final differentiation of B cells into immunoglobulin-secreting cells, as well as inducing myeloma/plasmacytoma growth, nerve cell ...
Antileukemic drugs, anticancer drugs that are used to treat one or more types of leukemia, include: [1]. 6-Mercaptopurine; 6-Thioguanine; Arsenic trioxide; Asparaginase; Cladribine ...
It is an engineered protein combining interleukin-2 and ... denileukin diftitox was approved by the US Food and Drug Administration (FDA) for the treatment of ...