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  2. Mirvetuximab soravtansine - Wikipedia

    en.wikipedia.org/wiki/Mirvetuximab_soravtansine

    Mirvetuximab soravtansine is indicated for the treatment of adults with folate receptor alpha (FRα) positive, platinum-resistant epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer, who have received one to three prior systemic treatment regimens. [2] [5] [6] Recipients are selected for therapy based on an FDA ...

  3. Ascendis to Present First Results from Platinum-Resistant ...

    lite.aol.com/tech/story/0022/20240913/9230274.htm

    COPENHAGEN, Denmark, Sept. 13, 2024 (GLOBE NEWSWIRE) -- Ascendis Pharma A/S (Nasdaq: ASND) today announced initial data showing signs of clinical activity in heavily pre-treated patients with platinum-resistant ovarian cancer (PROC) treated with TransCon IL-2 β/γ in combination with chemotherapy in its ongoing Phase 1/2 IL-Believe Trial of ...

  4. Altretamine - Wikipedia

    en.wikipedia.org/wiki/Altretamine

    The precise mechanism by which altretamine exerts its anti-cancer effect is unknown but it is classified by MeSH as an alkylating antineoplastic agent. [5] This unique structure is believed to damage tumor cells through the production of the weakly alkylating species formaldehyde, a product of CYP450-mediated N-demethylation. Administered ...

  5. Ovarian cancer - Wikipedia

    en.wikipedia.org/wiki/Ovarian_cancer

    If ovarian cancer recurs, it is considered partially platinum-sensitive or platinum-resistant, based on the time since the last recurrence treated with platins: partially platinum-sensitive cancers recurred 6–12 months after last treatment, and platinum-resistant cancers have an interval of less than 6 months.

  6. Vintafolide - Wikipedia

    en.wikipedia.org/wiki/Vintafolide

    Vintafolide is an investigational targeted cancer therapeutic currently under development by Endocyte and Merck & Co. [1] It is a small molecule drug conjugate consisting of a small molecule targeting the folate receptor, which is overexpressed on certain cancers, such as ovarian cancer, and a potent chemotherapy drug, vinblastine.

  7. Most-Watched Television Networks: Ranking 2024’s Winners and ...

    www.aol.com/most-watched-television-networks...

    Below are the primetime rankers for broadcast, cable and premium cable networks in 2024, among total viewers (as well as the top 50 list in adults 18-49).

  8. Trump will not rule out force to take Panama Canal, Greenland

    www.aol.com/news/trump-wont-rule-military...

    U.S. President-elect Donald Trump refused on Tuesday to rule out using military or economic action to pursue acquisition of the Panama Canal and Greenland, part of a broader expansionist agenda he ...

  9. Shaquille O'Neal Explains How He Maintains All of His Many ...

    www.aol.com/shaquille-oneal-explains-maintains...

    Celebrities, kids, fans, random people in the toy store — they've all got a friend in Shaquille O'Neal. As O'Neal, 52, gears up for his annual Shaq's Fun House party during Super Bowl weekend ...

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