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Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [2] [3] [4]Salts of this anion, especially docusate sodium, are widely used in medicine as an emollient laxative and as stool softeners, by mouth or rectally. [1]
Emollient laxatives, also known as stool softeners, are anionic surfactants that enable additional water and fats to be incorporated in the stool, making movement through the bowels easier. Properties. Site of action: small and large intestines; Onset of action: 12–72 hours; Examples: Docusate (Colace, Diocto), Gibs-Eze [3]
Sodium picosulfate is a prodrug. [5] It has no significant direct physiological effect on the intestine; however, it is metabolised by gut bacteria into the active compound 4,4'-dihydroxydiphenyl-(2-pyridyl)methane (DPM, BHPM).
A caplet is a smooth, coated, oval-shaped medicinal tablet in the general shape of a capsule. Many caplets have an indentation running down the middle, so they may be split in half more easily. [5] Consumers have viewed capsules as the most effective way to take medication ever since they first appeared.
Bottles are commonly used for liquid pharmaceuticals as well as formed tablets and capsules. Glass is most common for liquids because it is inert and has excellent barrier properties. Various types of plastic bottles are used both by drug producers as well as by pharmacists in a pharmacy.
Lactulose may be used to counter the constipating effects of opioids, and in the symptomatic treatment of hemorrhoids as a stool softener. [medical citation needed] Lactulose is commonly prescribed for children who develop fear of their bowel movements and are withholders.
Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. [1] [5] The medication is taken by mouth or via the rectum.
Dulcolax Stool Softener, a trade name of dioctyl sodium sulfosuccinate, a common ingredient in products such as laxatives Dulcolax SP Drops, a trade name of sodium picosulfate , a stimulant laxative drug.
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