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  2. Pyramidal inversion - Wikipedia

    en.wikipedia.org/wiki/Pyramidal_inversion

    In chemistry, pyramidal inversion (also umbrella inversion) is a fluxional process in compounds with a pyramidal molecule, such as ammonia (NH 3) "turns inside out". [1] [2] It is a rapid oscillation of the atom and substituents, the molecule or ion passing through a planar transition state. [3]

  3. Alkanolamine - Wikipedia

    en.wikipedia.org/wiki/Alkanolamine

    2-Aminoalcohols are an important class of organic compounds that are often generated by the reaction of amines with epoxides: C 2 H 4 O + R−NH 2 → RNHC 2 H 4 OH. Simple alkanolamines are used as solvents, synthetic intermediates, and high-boiling bases. [2] Hydrogenation or hydride reduction of amino acids gives the corresponding 2 ...

  4. Amine - Wikipedia

    en.wikipedia.org/wiki/Amine

    Amine. In chemistry, amines (/ ə ˈ m iː n, ˈ æ m iː n /, [1] [2] UK also / ˈ eɪ m iː n / [3]) are compounds and functional groups that contain a basic nitrogen atom with a lone pair.Formally, amines are derivatives of ammonia (NH 3 (in which the bond angle between the nitrogen and hydrogen is 170°), wherein one or more hydrogen atoms have been replaced by a substituent such as an ...

  5. Hofmann rearrangement - Wikipedia

    en.wikipedia.org/wiki/Hofmann_rearrangement

    The Hofmann rearrangement (Hofmann degradation) is the organic reaction of a primary amide to a primary amine with one less carbon atom. [1] [2] [3] The reaction involves oxidation of the nitrogen followed by rearrangement of the carbonyl and nitrogen to give an isocyanate intermediate.

  6. Heterocyclic amine - Wikipedia

    en.wikipedia.org/wiki/Heterocyclic_amine

    Niacin, essential to many types of life, is an example of a heterocyclic amine. Heterocyclic amines , also sometimes referred to as HCA s, are chemical compounds containing at least one heterocyclic ring, which by definition has atoms of at least two different elements, as well as at least one amine (nitrogen-containing) group.

  7. N,N-Diisopropylethylamine - Wikipedia

    en.wikipedia.org/wiki/N,N-Diisopropylethylamine

    N,N-Diisopropylethylamine, or Hünig's base, is an organic compound that is a tertiary amine. It is named after the German chemist Siegfried Hünig . It is used in organic chemistry as a non-nucleophilic base. It is commonly abbreviated as DIPEA, DIEA, or i-Pr 2 NEt.

  8. Amination - Wikipedia

    en.wikipedia.org/wiki/Amination

    Usually, the amine reacts as the nucleophile with another organic compound acting as the electrophile. This sense of reactivity may be reversed for some electron-deficient amines, including oxaziridines, hydroxylamines, oximes, and other N–O substrates. When the amine is used as an electrophile, the reaction is called electrophilic amination.

  9. Amino radical - Wikipedia

    en.wikipedia.org/wiki/Amino_radical

    In chemistry, the amino radical, ·NH 2, also known as the aminyl or azanyl, is the neutral form of the amide ion (NH − 2). Aminyl radicals are highly reactive and consequently short-lived, like most radicals; however, they form an important part of nitrogen chemistry. In sufficiently high concentration, amino radicals dimerise to form hydrazine