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Other mucus-secreting cells are the mucous neck cells in the necks of the gastric glands. [2]: 257 Surface mucous cells have large quantities of mucin granules in their apical (top) surface and project short microvilli into the lumen of the stomach. [2]: 257 Mucins are large glycoproteins that give the mucus its gel-like properties. [3]
Mucositis is the painful inflammation and ulceration of the mucous membranes lining the digestive tract, usually as an adverse effect of chemotherapy and radiotherapy treatment for cancer. [1] Mucositis can occur anywhere along the gastrointestinal (GI) tract, but oral mucositis refers to the particular inflammation and ulceration that occurs ...
It arises from epithelial cells that line certain internal organs and skin, and produce mucin (the main component of mucus). A malignant mucinous neoplasm is called a mucinous carcinoma. For example, for ovarian mucinous tumors, approximately 75% are benign, 10% are borderline and 15% are malignant.
The first cells of all of the glands are mucus-secreting foveolar cells that line the gastric pits. The mucus produced here is less acidic than that produced by the mucous neck cells. Fundic glands found in the fundus and also in the body have another two cell types–gastric chief cells and parietal cells (oxyntic cells).
Stomach cancer, also known as gastric cancer, is a malignant tumor of the stomach. It's a cancer that develops from the lining of the stomach . [ 10 ] Most cases of stomach cancers are gastric carcinomas , which can be divided into a number of subtypes, including gastric adenocarcinomas . [ 2 ]
Pseudomyxoma peritonei (PMP) is a clinical condition caused by cancerous cells (mucinous adenocarcinoma) that produce abundant mucin or gelatinous ascites. [1] The tumors cause fibrosis of tissues and impede digestion or organ function, and if left untreated, the tumors and mucin they produce will fill the abdominal cavity.
The sodium-iodide symporter (SIP) is expressed in all the surface mucous cells (at the basolateral membrane) but not in the mucous neck cells. SIP mediates the transport of iodide from the bloodstream and secretes it into the gastric lumen where it is taken up in the gastric juice. Its role is not known but it has been shown to be absent in ...
Primary SRCC tumors are most often found in the glandular cells of the stomach (SRCC originates in the stomach in 56 percent of patients), [2] and less frequently in the breast, gallbladder, urinary bladder, and pancreas. [3] SRCCs do not normally form in the lungs, though a few instances have been reported. [4]