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Jacob Tremblay (/ ˈ t r ɒ m b l eɪ / TROM-blay; born October 5, 2006) [1] is a Canadian actor. He became known for his role as a child born in captivity in Room (2015), for which he won the Critics' Choice Movie Award for Best Young Performer and became the youngest nominee for the Screen Actors Guild Award for Outstanding Performance by a Male Actor in a Supporting Role.
At birth he was deaf, and had head, facial, ear and skull deformities. At age 6 months he was diagnosed with Treacher Collins syndrome. At age 5 years he was referred to Shriners Hospitals for Children where he met with Dr. Lucie Lessard. [1] At age 6 (2003) he received a bone anchored hearing aid and discovered his passion for singing.
Treacher Collins syndrome is inherited in an autosomal-dominant pattern. Mutations in TCOF1, POLR1C, or POLR1D genes can cause Treacher Collins syndrome. [17] TCOF1 gene mutations are the most common cause of the disorder, with POLR1C and POLR1D gene mutations causing an additional 2% of cases. In individuals without an identified mutation in ...
Amanda Moreno Leighton [1] (born June 7, 1993 [2]) is an American actress.She is known for her voice acting as Blossom in the 2016 Cartoon Network animated series The Powerpuff Girls, Poppy in the 2018 Netflix animated series Trolls: The Beat Goes On!, and Polly Plantar in the 2019 Disney Channel animated series Amphibia.
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Researchers have found that most patients with Treacher Collins syndrome have symmetric external ear canal abnormalities and symmetrically dysmorphic or absent ossicles in the middle ear space. Inner ear structure is largely normal. Most patients show a moderate hearing impairment or greater, and the type of loss is generally a conductive ...
Beyoncé and Blue Ivy, Karlie Kloss and Joshua Kushner, DJ Khaled, Diddy, Chris Rock and Cardi B were just some of the celebs at the 2018 NBA All-Star Game.