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Ceftriaxone and azithromycin are each used to combat numerous other infections; and the more they are used, the more opportunity gonorrhea has to develop resistance to them.
Neisseria gonorrhoeae, the bacterium that causes the sexually transmitted infection gonorrhea, has developed antibiotic resistance to many antibiotics. The bacteria was first identified in 1879. [1] In the 1940s effective treatment with penicillin became available, but by the 1970s resistant strains predominated.
The preferred form of treatment for uncomplicated gonorrhea is a single intramuscular (IM) injection of an antibiotic called ceftriaxone. The injection is given into the upper part of the buttocks.
Ceftriaxone by injection and azithromycin by mouth [ 4 ][ 5 ] Frequency. 0.8% (women), 0.6% (men) [ 6 ] Gonorrhoea or gonorrhea, colloquially known as the clap, is a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae. [ 1 ] Infection may involve the genitals, mouth, or rectum. [ 7 ]
Cefixime, sold under the brand name Suprax among others, is an antibiotic medication used to treat a number of bacterial infections. [5] These infections include otitis media, strep throat, pneumonia, urinary tract infections, gonorrhea, and Lyme disease. [5] For gonorrhea typically only one dose is required. [6]
Ceftriaxone, sold under the brand name Rocephin, is a third-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. [4] These include middle ear infections, endocarditis, meningitis, pneumonia, bone and joint infections, intra-abdominal infections, skin infections, urinary tract infections, gonorrhea, and pelvic inflammatory disease. [4]
Since August 2012, the third-generation cephalosporin, ceftriaxone, is the only recommended treatment for gonorrhea in the United States (in addition to azithromycin or doxycycline for concurrent Chlamydia treatment). Cefixime is no longer recommended as a first-line treatment due to evidence of decreasing susceptibility. [30] Ceftriaxone ...
Cefpodoxime is an oral, third-generation cephalosporin antibiotic available in various generic preparations. It is active against both Gram-positive and Gram-negative organisms with notable exceptions including Pseudomonas aeruginosa, Enterococcus, and Bacteroides fragilis. It is typically used to treat acute otitis media, pharyngitis ...