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An immortalised cell line is a population of cells from a multicellular organism that would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division.
TF-1 cells are an immortal cell line derived from the human Erythroleukemia used in biomedical research. [1] This cells are proliferatively responsive to interleukin-3 (IL-3) or granulocyte-macrophage colony-stimulating factor (GM-CSF). [2] TF-1 cells have gene fusion of CBFA2T3-ABHD12. [3]
In cellular biology, stable cells are cells that multiply only when needed. They spend most of the time in the quiescent G 0 phase of the cell cycle but can be stimulated to enter the cell cycle when needed. Examples include the liver, the proximal tubules of the kidney and endocrine glands.
Cell engineering is the purposeful process of adding, deleting, or modifying genetic sequences in living cells to achieve biological engineering goals such as altering cell production, changing cell growth and proliferation requirements, adding or removing cell functions, and many more.
SH-SY5Y is a human derived cell line used in scientific research. The original cell line, called SK-N-SH, from which it was subcloned was isolated from a bone marrow biopsy taken from a four-year-old female with neuroblastoma. SH-SY5Y cells are often used as in vitro models of neuronal function and
Labile cells continually regenerate by undergoing mitosis and are one of three types of cells that are involved in cell division, classified by their regenerative capacity. [citation needed] The other two cell types include stable cells and permanent cells. Each of these three cell types respond to injuries to their corresponding tissues ...
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