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Rebound insomnia is insomnia that occurs following discontinuation of sedative substances taken to relieve primary insomnia. Regular use of these substances can cause a person to become dependent on its effects in order to fall asleep.
There is also evidence that antidepressant discontinuation syndrome may be related to the biological half-life of both SSRIs [24] and antidepressants in general. Antidepressants with a lower half-life, such as paroxetine , duloxetine , and venlafaxine , have been implicated in higher incidences of withdrawal symptoms and more severe withdrawal ...
A 2012 review focused on antidepressants and sleep found that mirtazapine reduced the time it took to fall asleep and improved the quality of sleep in many people with sleep disorders caused by depression, but that it could also disturb sleep in many people, especially at higher doses, causing restless leg syndrome in 8 to 28% of people and in ...
Elderly people are more sensitive to these side-effects. [174] Some benzodiazepines have demonstrated effectiveness in sleep maintenance in the short term but in the longer term benzodiazepines can lead to tolerance , physical dependence , benzodiazepine withdrawal syndrome upon discontinuation, and long-term worsening of sleep, especially ...
This situation is becoming more prevalent in western society due to the modern demands and expectations placed upon the individual. [8] Many medications can lead to secondary hypersomnia. Therefore, a patient's complete medication list should be carefully reviewed for sleepiness or fatigue as side effects.
When a person struggles to fall asleep or stay asleep without any obvious cause, it is referred to as insomnia, [2] which is the most common sleep disorder. [3] Other sleep disorders include sleep apnea , narcolepsy , hypersomnia (excessive sleepiness at inappropriate times), sleeping sickness (disruption of the sleep cycle due to infection ...
Paroxetine may produce discontinuation-related symptoms at a greater rate than other SSRIs, though qualitatively similar effects have been reported for all SSRIs. [181] [182] Discontinuation effects appear to be less for fluoxetine, perhaps owing to its long half-life and the natural tapering effect associated with its slow clearance from the ...
Subjects undergo a series of five 20-minute sleeping opportunities with an absence of alerting factors at 2-hour intervals on one day. The test is based on the idea that the sleepier people are, the faster they will fall asleep. [15] [16] The Maintenance of Wakefulness Test (MWT) is also used to quantitatively assess daytime sleepiness. This ...
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