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Antibiotic synergy is desirable in a clinic sense for several reasons. At the patient level, the boosted antimicrobial potency provided by synergy allows the body to more rapidly clear infections, resulting in shorter courses of antibiotic therapy. [3] Shorter courses of therapy in turn reduce the effects of dose-related toxicity, if applicable ...
Additive effect can be used to detect synergy as it can be considered as the baseline effect in methods determining whether drugs have synergistic effect. Synergistic effect is similar to additive effect, having a combination effect greater than additive effect. It can produce an effect of 2+2 > 4 when two drugs are used together.
Synergy is an interaction or cooperation giving rise to a whole that is greater than the simple sum of its parts (i.e., a non-linear addition of force, energy, or effect). [1]
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds:
Topics of pharmacodynamics. Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection).
Microbial synergy is a phenomenon in which aerobic and anaerobic microbes support each other's growth and proliferation. In this process aerobes invade and destroy host tissues, reduce tissue oxygen concentration and redox potential , thus creating favorable conditions for anaerobic growth and proliferation.
Broadly, a synergist is an entity that displays synergy with respect to another entity. More specifically, a synergist may be: a synergist muscle; a substance that enhances the effect of another substance, such as a drug (see Synergy § Biological sciences) something relating to the theological position of synergism
The opposite of antagonism is synergy. It is a negative type of synergism. It is a negative type of synergism. Experiments with different combinations show that binary mixtures of phenolics can lead to either a synergetic antioxidant effect or to an antagonistic effect.