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A polygene is a member of a group of non-epistatic genes that interact additively to influence a phenotypic trait, thus contributing to multiple-gene inheritance (polygenic inheritance, multigenic inheritance, quantitative inheritance [1]), a type of non-Mendelian inheritance, as opposed to single-gene inheritance, which is the core notion of ...
The infinitesimal model, also known as the polygenic model, is a widely used statistical model in quantitative genetics and in genome-wide association studies.Originally developed in 1918 by Ronald Fisher, it is based on the idea that variation in a quantitative trait is influenced by an infinitely large number of genes, each of which makes an infinitely small (infinitesimal) contribution to ...
In genetics, a polygenic score (PGS) is a number that summarizes the estimated effect of many genetic variants on an individual's phenotype. The PGS is also called the polygenic index (PGI) or genome-wide score; in the context of disease risk, it is called a polygenic risk score (PRS or PR score [1]) or genetic risk score. The score reflects an ...
The compression ratio of the micropump as one of the critical performance indicator is defined as the ratio between the stroke volume, i.e. fluid volume displaced by the pump membrane over the course of the pump cycle, and the dead volume, i.e. the minimum fluid volume remaining in the pump chamber in pumping mode. [15]
Very few phenotypes are purely Mendelian traits. Common violations of the Mendelian model include incomplete dominance, codominance, genetic linkage, environmental effects, and quantitative contributions from a number of genes (see: gene interactions, polygenic inheritance, oligogenic inheritance). [1] [2]
Diesel exhaust fluid (DEF; also known as AUS 32 and sometimes marketed as AdBlue [3]) is a liquid used to reduce the amount of air pollution created by a diesel engine. Specifically, DEF is an aqueous urea solution made with 32.5% urea and 67.5% deionized water .
If an NPSH A is say 10 bar then the pump you are using will deliver exactly 10 bar more over the entire operational curve of a pump than its listed operational curve. Example: A pump with a max. pressure head of 8 bar (80 metres) will actually run at 18 bar if the NPSH A is 10 bar. i.e.: 8 bar (pump curve) plus 10 bar NPSH A = 18 bar.
A molecular drag pump is a type of vacuum pump that utilizes the drag of air molecules against a rotating surface. [1] The most common sub-type is the Holweck pump, which contains a rotating cylinder with spiral grooves which direct the gas from the high vacuum side of the pump to the low vacuum side of the pump. [2]
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