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Sucralfate is a locally acting substance that in an acidic environment (pH < 4) reacts with hydrochloric acid in the stomach to form a cross-linking, viscous, paste-like material capable of acting as an acid buffer for as long as 6 to 8 hours after a single dose. [29]
[1] [2] [3] Subgroup J01 is part of the anatomical group J Antiinfectives for systemic use. [4] Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QJ01. [5] ATCvet codes without corresponding human ATC codes are cited with the leading Q in the following list.
ATC code A02 Drugs for acid related disorders is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
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In healthy humans, the half-life of PPIs is about 1 hour (9 hours for tenatoprazole), but the duration of acid inhibition is 48 hours because of irreversible binding to the H,K-ATPase. [82] All the PPIs except tenatoprazole are rapidly metabolized in the liver by CYP enzymes (mostly by CYP2C19 and 3A4). [ 82 ]
An ideal transconductance amplifier in a voltage follower configuration behaves at the output like a resistor of value 1/g m, between a buffered copy of the input voltage and the output. If the follower is loaded by a single capacitor C , the voltage follower transfer function has a single pole with time constant C / g m , [ 5 ] or equivalently ...
[1] [9] [10] It is mainly used in the treatment of heartburn and peptic ulcers. [ 1 ] [ 10 ] [ 11 ] With the development of proton pump inhibitors, such as omeprazole, approved for the same indications, cimetidine is available as an over-the-counter formulation to prevent heartburn or acid indigestion, along with the other H2-receptor antagonists.
Gastric bypass is indicated for the surgical treatment of severe obesity, a diagnosis which is made when the patient is seriously obese, has been unable to achieve satisfactory and sustained weight loss by dietary efforts and has comorbid conditions that are either life-threatening or serious impairment to the quality of life.