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Conventional cryoprotectants are glycols (alcohols containing at least two hydroxyl groups), such as ethylene glycol [citation needed], propylene glycol and glycerol. Ethylene glycol is commonly used as automobile antifreeze; while propylene glycol has been used to reduce ice formation in ice cream.
Most antifreeze is made by mixing distilled water with additives and a base product, usually MEG (mono ethylene glycol) or MPG (mono propylene glycol). Ethylene glycol solutions first became available in 1926 and were marketed as "permanent antifreeze" since the higher boiling points provided advantages for summertime use as well as during cold ...
It is usually used with additives, like corrosion inhibitors and antifreeze. Antifreeze, a solution of a suitable organic chemical (most often ethylene glycol, diethylene glycol, or propylene glycol) in water, is used when the water-based coolant has to withstand temperatures below 0 °C, or when its boiling point has to be raised.
Propylene glycol plays a significant role in the application of a glycol chiller. For cooling in brewing, there are few processes where decreasing or maintaining temperature are important - like crash cooling a beer after fermentation, or keeping a steady temperature during fermentation (which generates heat), or cooling the wort after an ...
Estimates on the prevalence of propylene glycol allergy range from 0.8% (10% propylene glycol in aqueous solution) to 3.5% (30% propylene glycol in aqueous solution). [ 70 ] [ 71 ] [ 72 ] The North American Contact Dermatitis Group (NACDG) data from 1996 to 2006 showed that the most common site for propylene glycol contact dermatitis was the ...
Propylene glycol methyl ether (PGME or 1-methoxy-2-propanol) is an organic solvent with a wide variety of industrial and commercial uses. [3] Similar to other glycol ethers, it is used as a carrier/solvent in printing/writing inks and paints/coatings. It also finds use as an industrial and commercial paint stripper.
Polypropylene glycol is produced by ring-opening polymerization of propylene oxide. The initiator is an alcohol and the catalyst a base, usually potassium hydroxide. When the initiator is ethylene glycol or water the polymer is linear. With a multifunctional initiator like glycerine, pentaerythritol or sorbitol the polymer branches out ...
Ethylene glycol has been shown to be toxic to humans [16] and is also toxic to domestic pets such as cats and dogs. A toxic dose requiring medical treatment varies but is considered more than 0.1 mL per kg body weight (mL/kg) of pure substance. That is roughly 16 mL of 50% ethylene glycol for an 80 kg adult and 4 mL for a 20 kg child.