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For Human alphaherpesvirus 2, subclinical shedding may account for most of the transmission. [6] Studies on discordant partners (one infected, one not) show that the transmission rate is approximately 5 per 10,000 sexual contacts. [8] Atypical symptoms are often attributed to other causes, such as a yeast infection. [4] [9]
Worldwide, the rate of infection with herpes simplex virus—counting both HSV-1 and HSV-2—is around 90%. [1] Although many people infected with HSV develop labial or genital lesions ( herpes simplex ), the majority are either undiagnosed or display no physical symptoms—individuals with no symptoms are described as asymptomatic or as having ...
For HSV-2, subclinical shedding may account for most of the transmission. [11] Studies on discordant partners (one infected with HSV-2, one not) show that the transmission rate is approximately 5–8.9 per 10,000 sexual contacts, with condom usage greatly reducing the risk of acquisition. [13]
On an annual basis, without the use of antivirals or condoms, the transmission risk of HSV-2 from infected male to female is about 8–11%. [41] [46] This is believed to be due to the increased exposure of mucosal tissue to potential infection sites. Transmission risk from infected female to male is around 4–5% annually. [46]
Genital herpes is a herpes infection of the genitals caused by the herpes simplex virus (HSV). [1] Most people either have no or mild symptoms and thus do not know they are infected. [ 1 ] When symptoms do occur, they typically include small blisters that break open to form painful ulcers . [ 1 ]
The two most common forms of herpes are caused by infection with herpes simplex virus (HSV). HSV-1 is typically acquired orally and causes cold sores; HSV-2 is usually acquired during sexual contact and affects the genitals; however, either strain may affect either site. [62] Some people are asymptomatic or have very mild symptoms.
is the average number of people infected from one other person. For example, Ebola has an of two, so on average, a person who has Ebola will pass it on to two other people.. In epidemiology, the basic reproduction number, or basic reproductive number (sometimes called basic reproduction ratio or basic reproductive rate), denoted (pronounced R nought or R zero), [1] of an infection is the ...
The trial, CAPRISA 004, was conducted among 889 women to evaluate the ability of 1% tenofovir gel to prevent male-to-female HIV transmission. The study found a 39% lower HIV infection rate in women using 1% tenofovir gel compared with women using a placebo gel. In addition, tenofovir gel was shown to be safe as tested. [21]
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