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Borage oil may contain the pyrrolizidine alkaloid amabiline, [6] [7] [8] which is hepatotoxic leading to a risk of liver damage. [1] Patients should use borage oil that is certified free of toxic unsaturated pyrrolizidine alkaloids (UPAs). [1] Consumption of 1-2 g of borage seed oil daily can result in an intake of toxic UPAs approaching 10 ug. [1]
Oenothera biennis, the common evening-primrose, [3] is a species of flowering plant in the family Onagraceae, native to eastern and central North America, from Newfoundland west to Alberta, southeast to Florida, and southwest to Texas, and widely naturalized elsewhere in temperate and subtropical regions. [4]
The evening primrose flower (O. biennis) produces an oil containing a high content of γ-linolenic acid, a type of omega−6 fatty acid.Omega−6 fatty acids (also referred to as ω−6 fatty acids or n−6 fatty acids) are a family of polyunsaturated fatty acids (PUFA) that share a final carbon-carbon double bond in the n−6 position, that is, the sixth bond, counting from the methyl end.
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The main phytochemical in this evening primrose seed oil is gamma-linolenic acid. [21] There is no high-quality scientific evidence that O. biennis or evening primrose oil has any effect on human diseases or promotion of health, [21] [22] and specifically no evidence that it is effective to treat atopic dermatitis or cancer.
Borage seed oil, blackcurrant seed oil, and evening primrose oil all have a significant amount of gamma-Linolenic acid (GLA) (about 23%, 15–20% and 7–10%, respectively), and it is this that has drawn the interest of researchers. Açaí oil, from the fruit of several species of the Açaí palm (Euterpe) grown in the Amazon region. [54] [55]
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Oenothera villosa, the hairy evening primrose, is a species of flowering plant in the family Onagraceae. [2] It is native to nearly all of the United States (except Hawaii, Alaska, Louisiana, Florida, and South Carolina), and to all Canadian provinces and the Northwest Territories.
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