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Drug-resistant Candida auris spread ‘worrisome’ say epidemiologists A CDC warning and a fungus spreading: Everything we know about the deadly candida auris Skip to main content
Petri dish of candida auris in a laboratory. (Getty Images) A drug-resistant and potentially deadly fungus has been spreading rapidly through U.S. health care facilities, a new government study finds.
Candida auris cases have skyrocketed in this country since 2019. Some strains are now resistant to common treatments. In 2017, the Centers for Disease Control and Prevention named Candida auris a ...
Invasive candidiasis is an infection (candidiasis) that can be caused by various species of Candida yeast. Unlike Candida infections of the mouth and throat (oral candidiasis) or vagina (Candidal vulvovaginitis), invasive candidiasis is a serious, progressive, and potentially fatal infection that can affect the blood (), heart, brain, eyes, bones, and other parts of the body.
Candida auris has attracted increased clinical attention because of its multiple drug resistance. [6] [7] [4]In vitro, more than 90% of C. auris isolates are resistant to fluconazole [8] [9] and a range of 3–73% of C. auris isolates are resistant to voriconazole, [9] [10] while other triazoles (posaconazole, itraconazole, and isavuconazole) display better activity.
Candidiasis is a fungal infection due to any species of the genus Candida (a yeast). [4] When it affects the mouth, in some countries it is commonly called thrush. [3] Signs and symptoms include white patches on the tongue or other areas of the mouth and throat. [3]
Candida auris infections rose more than eightfold in the U.S. between 2017 and 2021, according to the Centers for Disease Control and Prevention — from 171 annual cases to 1,420.
The side effects of oral treatment are significant and people without an infection should not take these drugs. [36] Azoles are the group of antifungals which act on the cell membrane of fungi. They inhibit the enzyme 14-alpha-sterol demethylase, a microsomal CYP, which is required for the biosynthesis of ergosterol for the cytoplasmic membrane.