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If cranial leaks last more than seven days, the chances of developing meningitis are significantly higher. [55] Spinal CSF leaks cannot result in meningitis due to the sterile conditions of the leak site. [24] When a CSF leak occurs at the temporal bone, surgery becomes necessary in order to prevent infection and repair the leak. [56]
Empty sella syndrome is the condition when the pituitary gland shrinks or becomes flattened, filling the sella turcica with cerebrospinal fluid instead of the normal pituitary. [2] It can be discovered as part of the diagnostic workup of pituitary disorders, or as an incidental finding when imaging the brain.
Since pharmacological therapy has had little effect on these tumors, a trans-sphenoidal surgery to remove part of the pituitary gland is the first treatment option. [5] TSH-secreting: Another rare condition only resulting in 1% of pituitary surgeries is a result of the increase in the secretion of the thyroid-stimulating hormone.
A cerebrospinal fluid (CSF) leak occurs in about 20% of cases and may result in fluid leaking from the nose or ear. [1] Meningitis occurs in about 14% of cases. [2] Other complications include injuries to the cranial nerves or blood vessels. [1] A basilar skull fracture typically requires a significant degree of trauma to occur. [1]
Autoimmune hypophysitis (or lymphocytic hypophysitis), inflammation of the pituitary gland due to autoimmunity. Nelson's syndrome, may occur after surgical removal of both adrenal glands, an out-dated method of treating Cushing's disease. Pituitary tumour, a tumor of the pituitary gland. Pituitary adenoma, a noncancerous tumor of the pituitary ...
Surgery is a common treatment for pituitary tumors. The normal approach is trans-sphenoidal adenectomy, which usually can remove the tumor without affecting the brain or optic nerves. [70] Radiation is also used to treat pituitary adenomas. Examples include external beam or proton beam radiation therapy or stereotactic radiosurgery.
Many pituitary tumors (25%) are found to have areas of hemorrhagic infarction on MRI scans, but apoplexy is not said to exist unless it is accompanied by symptoms. [1] [4] In some instances, lumbar puncture may be required if there is a suspicion that the symptoms might be caused by other problems (meningitis or subarachnoid hemorrhage).
The prevention of episodes of SCLS has involved two approaches. The earliest was advocated by the Mayo Clinic, and it recommended treatment with high doses of beta agonists such as terbutaline, phosphodiesterase-inhibitor theophylline, and leukotriene-receptor antagonists montelukast sodium. [10] [12]