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  2. Sodium channel blocker - Wikipedia

    en.wikipedia.org/wiki/Sodium_channel_blocker

    Sodium channel blockers are used in the treatment of cardiac arrhythmia. They are classified as "Type I" in the Vaughan Williams classification. Class I antiarrhythmic agents interfere with the (Na +) channel. Class I agents are grouped by their effect on the Na + channel, and by their effect on cardiac action potentials. Class I agents are ...

  3. Antiarrhythmic agent - Wikipedia

    en.wikipedia.org/wiki/Antiarrhythmic_agent

    Class I agents interfere with the sodium (Na +) channel. Class II agents are anti-sympathetic nervous system agents. Most agents in this class are beta blockers. Class III agents affect potassium (K +) efflux. Class IV agents affect calcium channels and the AV node. Class V agents work by other or unknown mechanisms.

  4. List of cardiac pharmaceutical agents - Wikipedia

    en.wikipedia.org/wiki/List_of_cardiac...

    Class of antihypertensives that bind to and inhibit the angiotensin II receptor type 1 and thereby block the arteriolar contraction and sodium retention effects of renin–angiotensin system. Azilsartan medoxomil

  5. Mexiletine - Wikipedia

    en.wikipedia.org/wiki/Mexiletine

    Common side effects include abdominal pain, chest discomfort, drowsiness, headache, and nausea. It works as a non-selective voltage-gated sodium channel blocker and belongs to the Class IB group of anti-arrhythmic medications. [2]

  6. Aprindine - Wikipedia

    en.wikipedia.org/wiki/Aprindine

    Aprindine is a Class 1b antiarrhythmic agent. [1] References This page was last edited on 12 January 2025, at 02:18 (UTC). Text is available under ...

  7. Category:Sodium channel blockers - Wikipedia

    en.wikipedia.org/wiki/Category:Sodium_channel...

    Pages in category "Sodium channel blockers" The following 77 pages are in this category, out of 77 total. This list may not reflect recent changes. A. Ajmaline;

  8. Nav1.8 - Wikipedia

    en.wikipedia.org/wiki/Nav1.8

    20264 Ensembl ENSG00000185313 ENSMUSG00000034533 UniProt Q9Y5Y9 Q6QIY3 RefSeq (mRNA) NM_001293306 NM_001293307 NM_006514 NM_001205321 NM_009134 RefSeq (protein) NP_001280235 NP_001280236 NP_006505 NP_001192250 NP_033160 Location (UCSC) Chr 3: 38.7 – 38.82 Mb Chr 9: 119.44 – 119.55 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Na v 1.8 is a sodium ion channel subtype that in ...

  9. Channel blocker - Wikipedia

    en.wikipedia.org/wiki/Channel_blocker

    A channel blocker is the biological mechanism in which a particular molecule is used to prevent the opening of ion channels in order to produce a physiological response in a cell. Channel blocking is conducted by different types of molecules, such as cations, anions, amino acids, and other chemicals.

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