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List of side effects of estradiol which may occur as a result of its use or have been associated with estrogen and/or progestogen therapy includes: [1] [2]. Gynecological: changes in vaginal bleeding, dysmenorrhea, increase in size of uterine leiomyomata, vaginitis including vaginal candidiasis, changes in cervical secretion and cervical ectropion, ovarian cancer, endometrial hyperplasia ...
Migraines in middle-aged women are primarily related to fluctuations in hormone levels; perimenopause causes a decline in estrogen, which triggers these very specific types of headaches in ...
The risk was highly age-dependent, with a rate of VTE of 2.1% in those less than 40 years of age and of 12% in those over 40 years of age. [161] In a subsequent study of 816 transgender women in whom the same regimen was used but transdermal estradiol had become the standard therapy for those over the age of 40, the risk of VTE was still ...
A decrease in estrogen levels can lead to osteoporosis, cognitive disorders, and can affect many important genes related to normal physiological function. [ citation needed ] Estrogen can be divided into four classes: 1) Animal Estrogens that includes estrone (E1), estradiol (E2), and estriol (E3); 2) Plant Estrogens ( Phytoestrogens ); 3 ...
In 2000, more than one in five women over 50 were taking hormones, according to statistics tracked by the Menopause Society, an influential health-care nonprofit. By 2008, fewer than 5 percent of ...
Other research has found that the rate of VTE is 1 to 5 in 10,000 woman-years in women who are not pregnant or taking a birth control pill, 3 to 9 in 10,000 woman-years in women who are on a birth control pill, 5 to 20 in 10,000 women-years in pregnant women, and 40 to 65 in 10,000 women-years in postpartum women. [104]
Average number of moderate-to-severe hot flashes per week with placebo and different doses of oral estradiol in menopausal women [40] [41]. Estradiol is used in menopausal hormone therapy to prevent and treat moderate to severe menopausal symptoms such as hot flashes, vaginal dryness and atrophy, and osteoporosis (bone loss). [11]
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